SCHEMBL30629451

NCCCC[C@H](NC(=O)[C@@H](N)CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	OPRD1	P41143	7/20	0.59

▸	OPRM1	P35372	5/20	0.59

▸	APLNR	P35414	1/20	0.48

▸	NTSR2	O95665	4/20	0.47

▸	NTSR1	P30989	3/20	0.47

▸	SORT1	Q99523	3/20	0.47

▸	SLC6A2	P23975	1/20	0.46

▸	BDKRB2	P30411	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30287598	0.97	OPRD1 (0.62)	OPRD1OPRM1NTSR2NTSR1SORT1
SCHEMBL30116347	0.97	OPRD1 (0.57)	OPRD1OPRM1APLNRNTSR2NTSR1
SCHEMBL30631183	0.96	OPRD1 (0.60)	OPRD1OPRM1NTSR2NTSR1SORT1
SCHEMBL30116351	0.95	OPRD1 (0.65)	OPRD1OPRM1NTSR2NTSR1SORT1
SCHEMBL30116350	0.95	OPRD1 (0.59)	OPRD1OPRM1APLNRNTSR2NTSR1
SCHEMBL30439763	0.94	OPRD1 (0.56)	OPRD1OPRM1BDKRB2
SCHEMBL30439569	0.93	OPRD1 (0.57)	OPRD1OPRM1BDKRB2
SCHEMBL30439746	0.93	OPRD1 (0.56)	OPRD1OPRM1NTSR2NTSR1SORT1
SCHEMBL30503059	0.93	OPRD1 (0.56)	OPRD1OPRM1NTSR2NTSR1SORT1
SCHEMBL29380576	0.93	OPRM1 (0.59)	OPRD1OPRM1NTSR2NTSR1SORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116635050-A	Novel triple agonists active on all of glucagon, GLP-1 and GIP receptors and uses thereof	韩美药品株式会社	2023-08-22	—	—	CN	disclosed