Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1160951 | 0.74 | PKM (0.64) | PTK2MAP4K4LMNAPKMNOTUM | |
| SCHEMBL16238083 | 0.74 | MAP4K4 (0.67) | PTK2MAP4K4LMNAPKMNOTUM | |
| SCHEMBL10768177 | 0.74 | PKM (0.78) | PTK2MAP4K4LMNAPKMNOTUM | |
| SCHEMBL4471892 | 0.74 | DHFR (0.49) | PTK2MAP4K4LMNAPKMNOTUM | |
| SCHEMBL17701253 | 0.71 | PTK2 (0.54) | PTK2MAP4K4LMNAPKMNOTUM | |
| SCHEMBL14879966 | 0.71 | PTK2 (0.58) | PTK2MAP4K4LMNAPKMNOTUM | |
| SCHEMBL6980508 | 0.71 | PKM (0.55) | PTK2MAP4K4LMNAPKMNOTUM | |
| SCHEMBL3160696 | 0.71 | MAP4K4 (0.62) | PTK2MAP4K4LMNAPKMNOTUM | |
| SCHEMBL17965559 | 0.71 | GAA (0.66) | PTK2MAP4K4LMNAPKMNOTUM | |
| SCHEMBL4012820 | 0.70 | IMPDH2 (0.42) | PTK2MAP4K4LMNAPKMNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116514799-A | Wee1 inhibitor, composition and application thereof | 星希尔生物科技(上海)有限公司 | 2023-08-01 | — | — | CN | disclosed |