Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 16/20 | 0.62 |
| ▸ | DRD2 | P14416 | 16/20 | 0.62 |
| ▸ | DRD4 | P21917 | 9/20 | 0.62 |
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3049243 | 0.93 | DRD3 (0.70) | DRD3DRD2DRD4TMEM97CA2 | |
| SCHEMBL3174390 | 0.87 | CA2 (0.63) | DRD3DRD2DRD4TMEM97CA2 | |
| SCHEMBL3046470 | 0.86 | DRD2 (0.69) | DRD3DRD2DRD4TMEM97CA2 | |
| SCHEMBL3049241 | 0.82 | DRD3 (0.71) | DRD3DRD2DRD4TMEM97CA2 | |
| SCHEMBL3059029 | 0.82 | REV1 (0.62) | TMEM97ABCB1 | |
| SCHEMBL3064376 | 0.81 | ABCB1 (0.67) | DRD3DRD2DRD4TMEM97CA2 | |
| SCHEMBL3054533 | 0.81 | DHCR7 (0.70) | DRD3DRD2DRD4TMEM97CA2 | |
| SCHEMBL3049007 | 0.80 | CA9 (0.86) | CA2CA9KDM4ETDP1ABCB1 | |
| SCHEMBL3051392 | 0.79 | CA2 (0.73) | DRD3DRD2DRD4TMEM97CA2 | |
| SCHEMBL3506177 | 0.79 | CA2 (0.73) | DRD3DRD2DRD4TMEM97CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394825-B2 | Compound | STERIX LIMITED (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222299-A1 | COMPOUND | MKI67, VHL, MYC | DRD3 3408/4885DRD2 2317/4885DRD4 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.