Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4074620 | 1.00 | KDM4E (0.57) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL17078728 | 0.86 | ALDH1A1 (0.54) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL4317587 | 0.86 | KDM4E (0.54) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL845125 | 0.86 | ALDH1A1 (0.62) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL17950860 | 0.84 | ALDH1A1 (0.40) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL18149317 | 0.84 | TSHR (0.52) | ALDH1A1KMT2AHSD17B10CASP1TSHR | |
| SCHEMBL21358055 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL20399076 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL6491004 | 0.81 | FTO (0.56) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL29416299 | 0.81 | KDM4E (0.70) | KDM4EALDH1A1GLAGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448510-A1 | INHIBITORS OF MET KINASE | Kinnate Biopharma Inc. (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114809-A1 | INHIBITORS OF MET KINASE | KINNATE BIOPHARMA INC. (US) | 2023-06-22 | — | — | WO | disclosed |