Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23639428 | 0.87 | ALDH1A1 (0.58) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL4074620 | 0.86 | KDM4E (0.57) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL30465486 | 0.86 | KDM4E (0.57) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL8545590 | 0.84 | TSHR (0.47) | ALDH1A1LMNAKMT2AHSD17B10TSHR | |
| SCHEMBL17078728 | 0.83 | ALDH1A1 (0.54) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL21358055 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL20399076 | 0.80 | KDM4E (0.50) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL7509912 | 0.79 | KDM4C (0.48) | KDM4EALDH1A1GAAL3MBTL1KMT2A | |
| SCHEMBL6491004 | 0.78 | FTO (0.56) | KDM4EALDH1A1GLAGAALMNA | |
| SCHEMBL68952 | 0.78 | KDM4E (0.70) | KDM4EALDH1A1GLAGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009137739-A1 | PROCESSES FOR THE PREPARATION OF O-[5-[4-AMINO-THIAZOL-2-YL]-PYRIDIN-2-YLMETHYL]-HYDROXYLAMINE | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-12 | — | — | WO | claimed |