Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 7/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NNMT | P40261 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14920974 | 0.88 | VNN1 (0.64) | VNN1HDAC1NPC1RAB9AKMT2A | |
| SCHEMBL11563704 | 0.88 | VNN1 (0.64) | VNN1HDAC1NPC1RAB9AKMT2A | |
| SCHEMBL17602245 | 0.83 | HDAC1 (0.57) | VNN1HDAC1NPC1RAB9AKMT2A | |
| SCHEMBL18286294 | 0.82 | VNN1 (1.00) | VNN1 | |
| SCHEMBL2308761 | 0.81 | NPC1 (0.68) | VNN1HDAC1NPC1RAB9AKMT2A | |
| SCHEMBL1060807 | 0.80 | HDAC1 (1.00) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL1503083 | 0.80 | ALDH1A1 (0.64) | VNN1HDAC1NPC1RAB9AKMT2A | |
| SCHEMBL30592887 | 0.79 | NPC1 (0.61) | VNN1HDAC1NPC1RAB9AKMT2A | |
| SCHEMBL21327511 | 0.79 | NPC1 (0.61) | VNN1HDAC1NPC1RAB9AKMT2A | |
| SCHEMBL30490235 | 0.79 | NNMT (0.59) | VNN1NNMTCA1CA2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4448510-A1 | INHIBITORS OF MET KINASE | Kinnate Biopharma Inc. (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114809-A1 | INHIBITORS OF MET KINASE | KINNATE BIOPHARMA INC. (US) | 2023-06-22 | — | — | WO | disclosed |