Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 8/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 8/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.34 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | NEK2 | P51955 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.34 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.34 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136596 | 1.00 | ACHE (0.39) | ACHEPARP10PARP11PARP1PIM1 | |
| SCHEMBL24136595 | 0.87 | ACHE (0.39) | ACHEPARP10PARP11PARP1PIM1 | |
| SCHEMBL30466416 | 0.86 | ACHE (0.43) | ACHEPARP10PARP11PARP1PIM1 | |
| SCHEMBL24136677 | 0.86 | ACHE (0.43) | ACHEPARP10PARP11PARP1PIM1 | |
| SCHEMBL24136634 | 0.86 | ACHE (0.43) | ACHEPARP10PARP11PARP1PIM1 | |
| SCHEMBL30046575 | 0.75 | PARP10 (0.35) | PARP10PARP11PARP1PIM1AURKB | |
| SCHEMBL24136647 | 0.75 | PARP10 (0.35) | PARP10PARP11PARP1PIM1AURKB | |
| SCHEMBL24136727 | 0.74 | IMPDH2 (0.37) | ACHEPARP10PARP11PARP1CDC7 | |
| SCHEMBL15830723 | 0.71 | PARP10 (0.44) | PARP10PARP11PARP1PIM1AURKB | |
| SCHEMBL15813912 | 0.71 | PARP1 (0.44) | ACHEPARP10PARP11PARP1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116194108-B | Novel dioxoisoquinolinone derivatives and use thereof | 韩美药品株式会社 | 2025-05-30 | — | — | CN | disclosed |
| CN-113423710-B | Novel heterocyclic tricyclic derivative compounds and use thereof | 韩美药品株式会社 | 2024-06-14 | — | — | CN | disclosed |
| CN-116194108-A | Novel dioxoisoquinolinone derivatives and use thereof | 韩美药品株式会社 | 2023-05-30 | — | — | CN | disclosed |