Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 7/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136596 | 0.87 | ACHE (0.39) | ACHEPARP10PARP11PARP1CDC7 | |
| SCHEMBL30466436 | 0.87 | ACHE (0.39) | ACHEPARP10PARP11PARP1CDC7 | |
| SCHEMBL24136634 | 0.86 | ACHE (0.43) | ACHEPARP10PARP11PARP1HTT | |
| SCHEMBL24136677 | 0.86 | ACHE (0.43) | ACHEPARP10PARP11PARP1CDC7 | |
| SCHEMBL30466416 | 0.86 | ACHE (0.43) | ACHEPARP10PARP11PARP1CDC7 | |
| SCHEMBL24136727 | 0.83 | IMPDH2 (0.37) | ACHEPARP10PARP11PARP1CDC7 | |
| SCHEMBL30466437 | 0.70 | PARP10 (0.42) | ACHEPARP10PARP11PARP1CDC7 | |
| SCHEMBL24136591 | 0.70 | PARP10 (0.42) | ACHEPARP10PARP11PARP1CDC7 | |
| SCHEMBL24136647 | 0.69 | PARP10 (0.35) | PARP10PARP11PARP1CDC7HTT | |
| SCHEMBL30046575 | 0.69 | PARP10 (0.35) | PARP10PARP11PARP1CDC7HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423710-B | Novel heterocyclic tricyclic derivative compounds and use thereof | 韩美药品株式会社 | 2024-06-14 | — | — | CN | disclosed |
| US-20220135582-A1 | NOVEL HETEROTRICYCLIC DERIVATIVE COMPOUND AND USE OF SAME | HANMI PHARMACEUTICAL CO., LTD. (KR) | 2022-05-05 | — | — | US | disclosed |
| EP-3929199-A1 | NOVEL HETEROTRICYCLIC DERIVATIVE COMPOUND AND USE OF SAME | Hanmi Pharmaceutical Co., Ltd. (KR) | 2021-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135582-A1 | NOVEL HETEROTRICYCLIC DERIVATIVE COMPOUND AND USE OF SAME | EZH2, EZH1, BMI1 | ACHE 4227/4885PARP10 499/4885PARP11 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.