Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 10/20 | 0.42 |
| ▸ | PARP1 | P09874 | 7/20 | 0.42 |
| ▸ | PARP11 | Q9NR21 | 6/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.37 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.37 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.37 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.37 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.37 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.37 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.37 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.37 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136591 | 1.00 | PARP10 (0.42) | PARP10PARP1PARP11ACHEADCY6 | |
| SCHEMBL24136746 | 0.81 | MAOA (0.39) | PARP10PARP1PARP11ACHEGRM5 | |
| SCHEMBL14854360 | 0.80 | PARP10 (0.42) | PARP10PARP1PARP11ACHEADCY6 | |
| SCHEMBL24136723 | 0.77 | ACHE (0.54) | PARP10PARP1PARP11ACHE | |
| SCHEMBL31012419 | 0.77 | ACHE (0.54) | PARP10PARP1PARP11ACHE | |
| SCHEMBL24136677 | 0.75 | ACHE (0.43) | PARP10PARP1PARP11ACHECDC7 | |
| SCHEMBL30466416 | 0.75 | ACHE (0.43) | PARP10PARP1PARP11ACHECDC7 | |
| SCHEMBL24681239 | 0.75 | PARP10 (0.44) | PARP10PARP1PARP11ACHEADCY6 | |
| SCHEMBL22713749 | 0.71 | PARP10 (0.47) | PARP10PARP1PARP11ACHEADCY6 | |
| SCHEMBL22713717 | 0.71 | PARP10 (0.44) | PARP10PARP1PARP11ACHEGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116194108-B | Novel dioxoisoquinolinone derivatives and use thereof | 韩美药品株式会社 | 2025-05-30 | — | — | CN | disclosed |
| CN-113423710-B | Novel heterocyclic tricyclic derivative compounds and use thereof | 韩美药品株式会社 | 2024-06-14 | — | — | CN | disclosed |
| CN-116194108-A | Novel dioxoisoquinolinone derivatives and use thereof | 韩美药品株式会社 | 2023-05-30 | — | — | CN | disclosed |