Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 6/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 15/20 | 0.49 |
| ▸ | PARP11 | Q9NR21 | 14/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.42 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24136723 | 1.00 | ACHE (0.54) | ACHEPARP1PARP10PARP11PARP15 | |
| SCHEMBL14842620 | 0.80 | ACHE (0.54) | ACHEPARP1PARP10PARP11 | |
| SCHEMBL30466437 | 0.77 | PARP10 (0.42) | ACHEPARP1PARP10PARP11 | |
| SCHEMBL24136591 | 0.77 | PARP10 (0.42) | ACHEPARP1PARP10PARP11 | |
| SCHEMBL30466416 | 0.72 | ACHE (0.43) | ACHEPARP1PARP10PARP11 | |
| SCHEMBL24136677 | 0.72 | ACHE (0.43) | ACHEPARP1PARP10PARP11 | |
| SCHEMBL10129821 | 0.70 | ACHE (0.50) | ACHEPARP1PARP10PARP11 | |
| SCHEMBL30402278 | 0.70 | ACHE (0.50) | ACHEPARP1PARP10PARP11 | |
| SCHEMBL24136646 | 0.69 | KDM4E (0.56) | ACHEPARP1PARP10PARP11 | |
| SCHEMBL29600821 | 0.69 | KDM4E (0.56) | ACHEPARP1PARP10PARP11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423710-B | Novel heterocyclic tricyclic derivative compounds and use thereof | 韩美药品株式会社 | 2024-06-14 | — | — | CN | disclosed |