Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18194397 | 1.00 | CA12 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL15730710 | 1.00 | CA12 (0.43) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL21157853 | 0.94 | HSD11B1 (0.46) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL18194392 | 0.93 | HSD11B1 (0.41) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL30719727 | 0.90 | HSD11B1 (0.40) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL21157238 | 0.90 | HSD11B1 (0.40) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL16664369 | 0.90 | HSD11B1 (0.40) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL22523881 | 0.89 | KIF11 (0.42) | CA12CA1CA2CA9HSD11B1 | |
| SCHEMBL17614162 | 0.88 | HTR6 (0.44) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL21726108 | 0.85 | CA2 (0.41) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109553634-B | Silicon-containing compound and organic electroluminescent device comprising the same | 三星显示有限公司 | 2023-06-23 | — | — | CN | disclosed |