Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25212021 | 0.92 | HTT (0.43) | FKBP1AHTTCPB1SMN1; SMN2NPC1 | |
| SCHEMBL30345251 | 0.84 | HTT (0.44) | FKBP1AHTTCPB1SMN1; SMN2NPC1 | |
| SCHEMBL31106346 | 0.84 | HTT (0.44) | FKBP1AHTTCPB1SMN1; SMN2NPC1 | |
| SCHEMBL25244077 | 0.79 | OPRK1 (0.33) | KMT2A | |
| SCHEMBL9546447 | 0.78 | HTR2C (0.57) | FKBP1AHTTCPB1SMN1; SMN2NPC1 | |
| SCHEMBL25213110 | 0.77 | ALDH1A1 (0.45) | FKBP1ASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL28782106 | 0.76 | HTR2C (0.49) | FKBP1AHTTCPB1SMN1; SMN2NPC1 | |
| SCHEMBL29816690 | 0.75 | HTR2C (0.48) | FKBP1AHTTCPB1SMN1; SMN2NPC1 | |
| SCHEMBL29816886 | 0.75 | HTR2C (0.48) | FKBP1AHTTCPB1SMN1; SMN2NPC1 | |
| SCHEMBL29816802 | 0.75 | HTR2C (0.48) | FKBP1AHTTCPB1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12545677-B2 | Compounds useful as factor XIa inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2026-02-10 | — | — | US | disclosed |
| EP-4185587-B1 | COMPOUNDS USEFUL AS FACTOR XIA INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-09-10 | — | — | EP | disclosed |
| CN-116133660-B | Compounds useful as factor XIa inhibitors | 詹森药业有限公司 | 2025-05-02 | — | — | CN | disclosed |
| US-20230312560-A1 | COMPOUNDS USEFUL AS FACTOR XIA INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-10-05 | — | — | US | disclosed |
| EP-4185587-A1 | COMPOUNDS USEFUL AS FACTOR XIA INHIBITORS | JANSSEN Pharmaceutica NV (BE) | 2023-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312560-A1 | COMPOUNDS USEFUL AS FACTOR XIA INHIBITORS | F11, F2, KLKB1 | FKBP1A 584/4885HTT 3234/4885CPB1 74/4885 |
| US-12545677-B2 | Compounds useful as factor XIa inhibitors | F2, F11, F10 | FKBP1A 192/4885HTT 2991/4885CPB1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.