Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21747463 | 0.87 | S1PR1 (0.47) | PDCD1CD274LMNAHTTALDH1A1 | |
| SCHEMBL30468304 | 0.86 | GPR119 (0.49) | GPR119IDO1TDO2IDO2PDCD1 | |
| SCHEMBL21747473 | 0.84 | NPC1 (0.44) | IDO1TDO2IDO2PDCD1CD274 | |
| SCHEMBL30468244 | 0.83 | ALDH1A1 (0.45) | IDO1TDO2IDO2LMNAHTT | |
| SCHEMBL30468309 | 0.81 | GPR119 (0.45) | GPR119IDO1TDO2IDO2PDCD1 | |
| SCHEMBL30468220 | 0.79 | HSD17B10 (0.44) | GPR119LMNAHTTTBK1MAPT | |
| SCHEMBL21747468 | 0.78 | PDCD1 (0.47) | PDCD1CD274ALDH1A1S1PR1S1PR3 | |
| SCHEMBL30468278 | 0.77 | HSD17B10 (0.53) | LMNAHTTALDH1A1MAPTTP53 | |
| SCHEMBL4859388 | 0.77 | MET (0.44) | METTBK1 | |
| SCHEMBL219656 | 0.77 | MET (0.44) | IDO1TDO2IDO2METS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613735-B1 | NOVEL SIRT 1 ACTIVATOR AND MEDICINAL USE THEREOF | NAT UNIV PUSAN IND UNIV COOP FOUND (KR) | 2023-04-12 | — | — | EP | disclosed |