Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 4/20 | 0.43 |
| ▸ | DRD5 | P21918 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2501566 | 0.87 | KDM1A (0.52) | ADRA2AHTR2CHTR2AHTR2BKDM1A | |
| SCHEMBL29051650 | 0.83 | HTR2C (0.53) | ADRA2AHTR2CHTR2AHTR2BKDM1A | |
| SCHEMBL1904887 | 0.81 | HTR2C (0.48) | ADRA2AHTR2CHTR2AHTR2BKDM1A | |
| SCHEMBL6651372 | 0.81 | HTR2C (0.48) | ADRA2AHTR2CHTR2AHTR2BKDM1A | |
| SCHEMBL6655706 | 0.77 | HTR2C (0.48) | ADRA2AHTR2CHTR2AHTR2BKDM1A | |
| SCHEMBL31317936 | 0.77 | HTR2C (0.60) | ADRA2AHTR2CHTR2AHTR2BDRD1 | |
| SCHEMBL225918 | 0.77 | HTR2C (0.60) | ADRA2AHTR2CHTR2AHTR2BDRD1 | |
| SCHEMBL2496854 | 0.77 | SIGMAR1 (0.52) | HTR2CHTR2AHTR2BKDM1A | |
| SCHEMBL29051809 | 0.76 | DRD2 (0.49) | HTR2CHTR2AHTR2BDRD1DRD5 | |
| SCHEMBL26922085 | 0.76 | KCNH2 (0.42) | ADRA2AHTR2CHTR2AHTR2BKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116332910-A | 2-aminopyrimidine derivatives as kinase inhibitors, preparation and use thereof | 江苏威凯尔医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |