Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | CCNC | P24863 | 2/20 | 0.35 |
| ▸ | CDK8 | P49336 | 2/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 2/20 | 0.35 |
| ▸ | CDK19 | Q9BWU1 | 2/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15129836 | 0.90 | KDM1A (0.39) | TSHRKDM1AMAPK14CCNCCDK8 | |
| SCHEMBL17444524 | 0.90 | KDM1A (0.43) | TSHRKDM1AMAPK14IP6K1SIRT2 | |
| SCHEMBL30898666 | 0.88 | TDP2 (0.45) | MAPK14CCNCCDK8EZH2PDK2 | |
| SCHEMBL31390939 | 0.85 | MAPK14 (0.43) | TSHRKDM1AMAPK14IP6K1SIRT2 | |
| SCHEMBL22058140 | 0.84 | KDM1A (0.40) | TSHRKDM1AMAPK14IP6K1SIRT2 | |
| Bromide SCHEMBL20954964 | 0.83 | KDM1A (0.39) | TSHRKDM1AMAPK14IP6K1SIRT2 | |
| SCHEMBL30460002 | 0.79 | KDM1A (0.43) | TSHRKDM1AMAPK14IP6K1SIRT2 | |
| SCHEMBL17436068 | 0.79 | PKM (0.50) | KDM4EALDH1A1 | |
| SCHEMBL17436008 | 0.77 | RARB (0.44) | KDM1ARARBRARGKDM4EALDH1A1 | |
| SCHEMBL30459971 | 0.77 | KDM1A (0.41) | TSHRKDM1AMAPK14IP6K1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110769821-B | Spiro indolines as IL-17 modulators | UCB生物制药有限责任公司 | 2023-07-07 | — | — | CN | disclosed |