Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | STK4 | Q13043 | 1/20 | 0.39 |
| ▸ | STK3 | Q13188 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898640 | 0.88 | TDP2 (0.46) | TDP2PDK2ERN1MAPK14BRD4 | |
| SCHEMBL30468541 | 0.88 | TSHR (0.40) | PDK2EZH2MAPK14BRD4CCNC | |
| SCHEMBL30898703 | 0.84 | TDP2 (0.46) | TDP2PDK2ERN1EZH2MAPK14 | |
| SCHEMBL30898648 | 0.79 | MAPK14 (0.56) | TDP2MAPK14 | |
| SCHEMBL15129836 | 0.79 | KDM1A (0.39) | PDK2MAPK14CCNCCDK8 | |
| SCHEMBL17444524 | 0.78 | KDM1A (0.43) | PDK2MAPK14BRD4 | |
| SCHEMBL30898683 | 0.78 | TDP2 (0.43) | TDP2STK4STK3LRRK2PDK2 | |
| SCHEMBL31390939 | 0.74 | MAPK14 (0.43) | PDK2MAPK14 | |
| SCHEMBL22058140 | 0.73 | KDM1A (0.40) | PDK2MAPK14 | |
| SCHEMBL30898644 | 0.73 | TDP2 (0.43) | TDP2STK4STK3LRRK2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113330008-B | Preparation method of amide compound and application of amide compound in medicine field | 上海华汇拓医药科技有限公司 | 2024-05-07 | — | — | CN | disclosed |