Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.45 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21729414 | 0.81 | RAPGEF4 (0.44) | RAPGEF4MAPTNOS1RXRARXRB | |
| SCHEMBL29557826 | 0.81 | RAPGEF4 (0.46) | RAPGEF4CYP1A2CYP3A4MAPTMAPK1 | |
| SCHEMBL27959140 | 0.81 | RAPGEF4 (0.46) | RAPGEF4CYP1A2CYP3A4MAPTMAPK1 | |
| SCHEMBL25968108 | 0.80 | RAPGEF4 (0.43) | RAPGEF4MAPTNOS1RXRARXRB | |
| SCHEMBL19668955 | 0.80 | RAPGEF4 (0.43) | RAPGEF4MAPTNOS1RXRARXRB | |
| SCHEMBL19645280 | 0.79 | RAPGEF4 (0.41) | RAPGEF4MAPTNOS1PGK1PGK2 | |
| SCHEMBL217204 | 0.78 | RAPGEF4 (0.47) | RAPGEF4CYP1A2CYP3A4MAPTMAPK1 | |
| SCHEMBL26745203 | 0.77 | RAPGEF4 (0.40) | RAPGEF4MAPTMAPK1NOS1PGK1 | |
| SCHEMBL41567 | 0.77 | CES2 (0.44) | RAPGEF4CYP3A4MAPTMAPK1RXRA | |
| SCHEMBL30509222 | 0.75 | CES2 (0.39) | RAPGEF4MAPTRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490528-A | Polymer compositions containing cyclics obtained using transition metal bis (phenoxide) catalyst complexes and process for their preparation | 埃克森美孚化学专利公司 | 2023-07-25 | — | — | CN | claimed |
| CN-116490528-A | Polymer compositions containing cyclics obtained using transition metal bis (phenoxide) catalyst complexes and process for their preparation | 埃克森美孚化学专利公司 | 2023-07-25 | — | — | CN | disclosed |