SCHEMBL217204

SCHEMBL217204

Cc1cc(C)c([NH+](C)C)c(C)c1.FC(F)(F)c1cc([B-](c2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc(C(F)(F)F)c1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 3/20 0.47
NOTUM Q6P988 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21729414 0.80 RAPGEF4 (0.44) RAPGEF4NOTUMMAPT
Trimethylammonium SCHEMBL219375 0.80 CES2 (0.38) RAPGEF4MAPT
SCHEMBL27959140 0.79 RAPGEF4 (0.46) RAPGEF4CYP1A2CYP3A4MAPTMAPK1
SCHEMBL29557826 0.79 RAPGEF4 (0.46) RAPGEF4CYP1A2CYP3A4MAPTMAPK1
SCHEMBL19668955 0.78 RAPGEF4 (0.43) RAPGEF4NOTUMMAPT
SCHEMBL25968108 0.78 RAPGEF4 (0.43) RAPGEF4NOTUMMAPT
SCHEMBL14152974 0.78 RAPGEF4 (0.40) RAPGEF4
SCHEMBL30468643 0.78 RAPGEF4 (0.45) RAPGEF4CYP1A2CYP3A4MAPTMAPK1
SCHEMBL19645280 0.78 RAPGEF4 (0.41) RAPGEF4NOTUMMAPT
SCHEMBL14977524 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 770 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114867758-B Metallocene and method thereof 埃克森美孚化学专利公司 2025-04-08 CN claimed
US-11760814-B2 1,5 diazabicyclooctane ligand systems and methods therewith EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-09-19 US claimed
EP-4222180-A1 BIS(HETEROCYCLIC-OLATE) LEWIS BASE CATALYSTS AND METHODS THEREOF ExxonMobil Chemical Patents Inc. (US) 2023-08-09 EP claimed
EP-4196507-A1 CYCLIC CONTAINING POLYMER COMPOSITIONS OBTAINED USING TRANSITION METAL BIS(PHENOLATE) CATALYST COMPLEXES AND PROCESS FOR PRODUCTION THEREOF ExxonMobil Chemical Patents Inc. (US) 2023-06-21 EP claimed
EP-4103631-A1 ETHYLENE-ALPHA-OLEFIN-DIENE MONOMER COPOLYMERS OBTAINED USING TRANSITION METAL BIS(PHENOLATE) CATALYST COMPLEXES AND HOMOGENEOUS PROCESS FOR PRODUCTION THEREOF ExxonMobil Chemical Patents Inc. (US) 2022-12-21 EP claimed
EP-4103629-A1 POLYETHYLENE COMPOSITIONS OBTAINED USING TRANSITION METAL BIS(PHENOLATE) CATALYST COMPLEXES AND HOMOGENEOUS PROCESS FOR PRODUCTION THEREOF ExxonMobil Chemical Patents Inc. (US) 2022-12-21 EP claimed
EP-4007780-A1 METALLOCENES AND METHODS THEREOF ExxonMobil Chemical Patents Inc. (US) 2022-06-08 EP claimed
US-11306162-B2 Metallocenes with two -Si-Si- bridges EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-04-19 US claimed
EP-3956370-A1 METALLOCENES WITH TWO -SI-SI-BRIDGES ExxonMobil Chemical Patents Inc. (US) 2022-02-23 EP claimed
US-11254763-B2 Transition metal bis(phenolate) complexes and their use as catalysts for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-02-22 US claimed
US-20050239981-A1 Phosphorus bridged metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2005-10-27 US claimed
US-20050239980-A1 Phosphorus substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2005-10-27 US claimed
EP-1546223-A2 SUPERCRITICAL POLYMERIZATION PROCESS AND POLYMERS PRODUCED THEREFROM ExxonMobil Chemical Patents Inc. (US) 2005-06-29 EP claimed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP claimed
US-20040266961-A1 Catalyst composition II EXXONMOBIL CHEMICAL PATENTS INC. 2004-12-30 US claimed
WO-2004106390-A2 POLYMERIZATION AND OLIGOMERIZATION CATALYST WITH TRIDENTATE OR TETRADENTATE LIGAND EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-12-09 WO claimed
WO-2004026923-A9 SUPERCRITICAL POLYMERIZATION PROCESS AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEM PATENTS INC (US) 2004-09-10 WO claimed
US-20040122191-A1 Supercritical polymerization process and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC 2004-06-24 US claimed
WO-2004026923-A2 SUPERCRITICAL POLYMERIZATION PROCESS AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-04-01 WO claimed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760814-B2 1,5 diazabicyclooctane ligand systems and methods therewith ODC1, DDT, OXGR1 RAPGEF4 543/4885NOTUM 54/4885CYP1A2 746/4885
US-11254763-B2 Transition metal bis(phenolate) complexes and their use as catalysts for olefin polymerization CCNT1, CCNA1, CCNE2 RAPGEF4 1566/4885NOTUM 3640/4885CYP1A2 2025/4885
US-20050239981-A1 Phosphorus bridged metallocene compounds for olefin polymerization PYM1, ZNF207, POLL RAPGEF4 853/4885NOTUM 2536/4885CYP1A2 3980/4885
US-20040266961-A1 Catalyst composition II MLX, CBX2, BMX RAPGEF4 4437/4885NOTUM 3950/4885CYP1A2 1139/4885
US-20050239980-A1 Phosphorus substituted metallocene compounds for olefin polymerization CCRL2, ARL1, OSBP2 RAPGEF4 546/4885NOTUM 3026/4885CYP1A2 2280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.