Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 3/20 | 0.64 |
| ▸ | PGR | P06401 | 3/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | LAP3 | P28838 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557354 | 1.00 | TDP2 (0.64) | TDP2PGRADORA1MAPTLMNA | |
| 2-Nitrofluorene SCHEMBL29450702 | 0.84 | MAPT (0.68) | TDP2PGRMAPTLMNAMEN1 | |
| 2-Nitrofluorene SCHEMBL644332 | 0.84 | MAPT (0.68) | TDP2PGRMAPTLMNAMEN1 | |
| 2-Nitrofluorene SCHEMBL28186600 | 0.83 | MAPT (0.62) | TDP2PGRMAPTLMNAMEN1 | |
| SCHEMBL7618863 | 0.81 | MAPT (0.58) | TDP2PGRMAPTLMNAMEN1 | |
| SCHEMBL12379603 | 0.80 | TDP2 (0.59) | TDP2PGRADORA1MAPTLMNA | |
| Fluorene SCHEMBL28402445 | 0.79 | ALDH1A1 (0.64) | MAPTLMNAMEN1KMT2ARAB9A | |
| 2-Nitrofluorene SCHEMBL28251179 | 0.79 | MAPT (0.60) | TDP2PGRMAPTLMNAMEN1 | |
| SCHEMBL3414807 | 0.79 | ALDH1A1 (0.63) | TDP2MAPTLMNAMEN1KMT2A | |
| SCHEMBL30395577 | 0.79 | ALDH1A1 (0.63) | TDP2MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283668-A | Diaryl ureas as CB1 allosteric modulators | 研究三角协会 | 2023-06-23 | — | — | CN | disclosed |