Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.58 |
| ▸ | TDP2 | O95551 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PTPRC | P08575 | 3/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | S100A4 | P26447 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | GPR3 | P46089 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Nitrofluorene SCHEMBL644332 | 1.00 | MAPT (0.68) | MAPTTLR9LMNARAB9AMEN1 | |
| 2-Nitrofluorene SCHEMBL28186600 | 0.95 | MAPT (0.62) | MAPTTLR9LMNARAB9AMEN1 | |
| 2-Nitrofluorene SCHEMBL28251179 | 0.94 | MAPT (0.60) | MAPTTLR9LMNARAB9AMEN1 | |
| SCHEMBL7618863 | 0.93 | MAPT (0.58) | MAPTTLR9LMNARAB9AMEN1 | |
| SCHEMBL12298162 | 0.92 | PTPRC (0.58) | MAPTTLR9LMNARAB9AMEN1 | |
| 2-Nitrofluorene SCHEMBL8006385 | 0.91 | MAPT (0.85) | MAPTTLR9LMNARAB9AMEN1 | |
| SCHEMBL30049268 | 0.91 | TLR9 (0.79) | MAPTTLR9LMNARAB9AMEN1 | |
| SCHEMBL987760 | 0.91 | TLR9 (0.79) | MAPTTLR9LMNARAB9AMEN1 | |
| 2-Nitrofluorene SCHEMBL7722767 | 0.89 | MAPT (0.56) | MAPTTLR9LMNARAB9AMEN1 | |
| 2-Nitrofluorene SCHEMBL28029750 | 0.89 | MAPT (0.56) | MAPTTLR9LMNARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624029-B2 | JAK inhibitor compounds, method for synthesizing same and use thereof | Galderma Holding SA (CH) | 2026-05-12 | — | — | US | disclosed |
| US-12606559-B2 | JAK inhibitor compounds, methods for synthesizing same and use thereof | Galderma Holding SA (CH) | 2026-04-21 | — | — | US | disclosed |
| US-12583868-B2 | JAK inhibitors and methods for synthesizing and using thereof | Galderma Holding SA (CH) | 2026-03-24 | — | — | US | disclosed |
| US-20250304564-A1 | NOVEL KV3 MODULATORS | AUTIFONY THERAPEUTICS LTD (GB) | 2025-10-02 | — | — | US | disclosed |
| US-20250268926-A1 | METHOD AND COMPOSITION FOR TREATING, ALLEVIATING OR PREVENTING A DISEASE OR CONDITION CAUSED BY AIR POLLUTANT | HONG KONG BAPTIST UNIVERSITY (CN) | 2025-08-28 | — | — | US | disclosed |
| US-20250263376-A1 | (E)-N-CINNAMOYLAMINOALKANOLS WITH MELANOGENESIS INHIBITORY ACTIVITY | UNIWERSYTET JAGIELLONSKI (PL) | 2025-08-21 | — | — | US | disclosed |
| US-12358901-B2 | KV3 modulators | AUTIFONY THERAPEUTICS LIMITED (GB) | 2025-07-15 | — | — | US | disclosed |
| EP-3883563-B1 | CANNABIDIOL-TYPE CANNABINOID COMPOUND | JAZZ PHARMACEUTICALS RESEARCH UK LTD (GB) | 2025-04-30 | — | — | EP | disclosed |
| US-20250129041-A1 | MOLECULAR GLUE AND USES THEREOF | ASTROGEN, INC. (KR) | 2025-04-24 | — | — | US | disclosed |
| WO-2025084740-A1 | NOVEL MOLECULAR ADHESIVE AND USE THEREOF | 주식회사 아스트로젠 | 2025-04-24 | — | — | WO | disclosed |
| EP-4185587-A1 | COMPOUNDS USEFUL AS FACTOR XIA INHIBITORS | JANSSEN Pharmaceutica NV (BE) | 2023-05-31 | — | — | EP | disclosed |
| US-20220383550-A1 | METHOD FOR ASSESSING ASSESSMENT TARGETS, IMAGE PROCESSING DEVICE, SYSTEM FOR ASSESSING ASSESSMENT TARGETS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-12-01 | — | — | US | disclosed |
| WO-2022223480-A1 | GREEN SOLVENTS FOR CHEMICAL REACTIONS | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2022-10-27 | — | — | WO | disclosed |
| EP-4056672-A1 | METHOD FOR ASSESSING ASSESSMENT TARGETS, IMAGE PROCESSING DEVICE, SYSTEM FOR ASSESSING ASSESSMENT TARGETS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2022-09-14 | — | — | EP | disclosed |
| CN-114324681-A | High-throughput method for detecting content of nitro polycyclic aromatic hydrocarbon | 南通市疾病预防控制中心 | 2022-04-12 | — | — | CN | disclosed |
| WO-2022072975-A1 | COMPOSITIONS AND METHODS OF TREATMENT FOR SARS-COV-2 THROUGH PAPAIN PROTEASE INHIBITION | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2022-04-07 | — | — | WO | disclosed |
| US-20220087992-A1 | COMPOUNDS AND METHODS OF TREATING RETINAL DEGENERATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-03-24 | — | — | US | disclosed |
| WO-2022054005-A1 | NOVEL JAK INHIBITOR COMPOUNDS, METHOD FOR SYNTHESIZING SAME AND USE THEREOF | Galderma Holding SA (CH) | 2022-03-17 | — | — | WO | disclosed |
| WO-2022054006-A1 | NOVEL JAK INHIBITOR COMPOUNDS, METHOD FOR SYNTHESIZING SAME AND USE THEREOF | Galderma Holding SA (CH) | 2022-03-17 | — | — | WO | disclosed |
| WO-2022053931-A1 | NOVEL JAK INHIBITOR COMPOUNDS, METHOD FOR SYNTHESIZING SAME AND USE THEREOF | Galderma Holding SA (CH) | 2022-03-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12358901-B2 | KV3 modulators | KCNN3, KCNA3, KCNH3 | MAPT 4712/4885TLR9 3197/4885LMNA 1599/4885 |
| US-20220087992-A1 | COMPOUNDS AND METHODS OF TREATING RETINAL DEGENERATION | ALDH1A2, PDE6D, PDE6C | MAPT 745/4885TLR9 3454/4885LMNA 884/4885 |
| US-20250263376-A1 | (E)-N-CINNAMOYLAMINOALKANOLS WITH MELANOGENESIS INHIBITORY ACTIVITY | TYR, MITF, MC1R | MAPT 4655/4885TLR9 4525/4885LMNA 1056/4885 |
| US-20250129041-A1 | MOLECULAR GLUE AND USES THEREOF | ILK, FGB, UNC119 | MAPT 655/4885TLR9 3652/4885LMNA 3193/4885 |
| US-12606559-B2 | JAK inhibitor compounds, methods for synthesizing same and use thereof | JAK2, JAK1, JAK3 | MAPT 4442/4885TLR9 1280/4885LMNA 3990/4885 |
| US-12624029-B2 | JAK inhibitor compounds, method for synthesizing same and use thereof | JAK2, JAK1, JAK3 | MAPT 4257/4885TLR9 1796/4885LMNA 4367/4885 |
| US-12583868-B2 | JAK inhibitors and methods for synthesizing and using thereof | JAK2, JAK1, JAK3 | MAPT 4346/4885TLR9 1699/4885LMNA 4003/4885 |
| US-20250304564-A1 | NOVEL KV3 MODULATORS | KCNN3, KCNA3, KCND3 | MAPT 4634/4885TLR9 3978/4885LMNA 1698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.