2-Nitrofluorene

2-Nitrofluorene

SCHEMBL644332

O=[N+]([O-])c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.68
TLR9 Q9NR96 2/20 0.68
LMNA P02545 2/20 0.68
RAB9A P51151 2/20 0.68
MEN1 O00255 1/20 0.68
KMT2A Q03164 1/20 0.68
HSP90AA1 P07900 2/20 0.58
TDP2 O95551 1/20 0.55
CYP1A2 P05177 2/20 0.55
HSD17B10 Q99714 1/20 0.55
PTPRC P08575 3/20 0.54
ACHE P22303 2/20 0.54
S100A4 P26447 2/20 0.54
BCHE P06276 1/20 0.54
CES1 P23141 1/20 0.54
PARP1 P09874 2/20 0.52
GPR3 P46089 1/20 0.51
CRHBP P24387 1/20 0.51
CRHR2 Q13324 1/20 0.51
ALDH1A1 P00352 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2-Nitrofluorene SCHEMBL29450702 1.00 MAPT (0.68) MAPTTLR9LMNARAB9AMEN1
2-Nitrofluorene SCHEMBL28186600 0.95 MAPT (0.62) MAPTTLR9LMNARAB9AMEN1
2-Nitrofluorene SCHEMBL28251179 0.94 MAPT (0.60) MAPTTLR9LMNARAB9AMEN1
SCHEMBL7618863 0.93 MAPT (0.58) MAPTTLR9LMNARAB9AMEN1
SCHEMBL12298162 0.92 PTPRC (0.58) MAPTTLR9LMNARAB9AMEN1
2-Nitrofluorene SCHEMBL8006385 0.91 MAPT (0.85) MAPTTLR9LMNARAB9AMEN1
SCHEMBL30049268 0.91 TLR9 (0.79) MAPTTLR9LMNARAB9AMEN1
SCHEMBL987760 0.91 TLR9 (0.79) MAPTTLR9LMNARAB9AMEN1
2-Nitrofluorene SCHEMBL7722767 0.89 MAPT (0.56) MAPTTLR9LMNARAB9AMEN1
2-Nitrofluorene SCHEMBL28029750 0.89 MAPT (0.56) MAPTTLR9LMNARAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1717 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113711007-B Method for determining generation source of microparticles in atmosphere 株式会社岛津制作所 2024-10-25 CN claimed
EP-4376823-A1 COMPOUNDS INHIBITING THE SYNERGISTIC CARSINOGENIC EFFECT OF HEAVY METALS IN THE PRESENCE OF OTHER CARCINOGENS FOR USE IN THE TREATMENT OF CANCER Cancer Research And Biotechnology Ag (CH) 2024-06-05 EP claimed
CN-117920223-A Application of magnetic iron-nickel spinel in preparation of aromatic amine compound by catalytic hydrogenation of aromatic nitro compound 兰州大学 2024-04-26 CN claimed
WO-2022243552-A1 COMPOUNDS INHIBITING THE SYNERGISTIC CARSINOGENIC EFFECT OF HEAVY METALS IN THE PRESENCE OF OTHER CARCINOGENS FOR USE IN THE TREATMENT OF CANCER CANCER RESEARCH AND BIOTECHNOLOGY AG (CH) 2022-11-24 WO claimed
US-20220214283-A1 METHOD FOR IDENTIFYING GENERATION SOURCES OF FINE PARTICULATES IN ATMOSPHERE SHIMADZU CORPORATION (JP) 2022-07-07 US claimed
CN-113960220-B Synchronous detection method and application of polycyclic aromatic hydrocarbon and derivatives thereof in blood 生态环境部华南环境科学研究所 2022-03-04 CN claimed
CN-113960220-A Synchronous detection method and application of polycyclic aromatic hydrocarbon and derivatives thereof in blood 生态环境部华南环境科学研究所 2022-01-21 CN claimed
CN-113711007-A Method for determining generation source of fine particles in atmosphere 株式会社岛津制作所 2021-11-26 CN claimed
CN-108484418-B Branched blue fluorescent molecules and preparation method and application thereof 华南理工大学 2021-07-20 CN claimed
CN-112680498-A High-throughput screening method for genotoxic substances 华南理工大学 2021-04-20 CN claimed
EP-0232167-A2 Photosensitive and high energy beam sensitive resin composition containing substituted polysiloxane NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1987-08-12 EP claimed
US-4626556-A LADDER POLYMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1986-12-02 US claimed
EP-0136679-A2 Photopolymerizable epoxy resin composition KABUSHIKI KAISHA TOSHIBA (JP) 1985-04-10 EP claimed
EP-0043480-B1 PROCESS FOR FORMING METALLIC IMAGES Hitachi, Ltd. (JP) 1985-04-03 EP claimed
US-4347304-A PHOTOSENSITIZATION WITH DISILANES OR ORGANIC COMPOUNDS HAVING COUPLED GERMANIUM OR TIN MOLECULES; PHOTORESISTS; POSITIVES; PLATING HITACHI, LTD. (JP) 1982-08-31 US claimed
US-4330612-A PHOTORESISTS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1982-05-18 US claimed
US-4321319-A Photosensitive compositions containing polyamides acid with photosensitive groups HITACHI, LTD. (JP) 1982-03-23 US claimed
EP-0043480-A2 Process for forming metallic images Hitachi, Ltd. (JP) 1982-01-13 EP claimed
US-4294908-A Photoresist composition containing modified cyclized diene polymers JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-10-13 US claimed
US-3948667-A HOMO- AND CO-POLYMERS OF CYCLIZED BUTADIENE AND A CROSSLINKING AGENT JAPAN SYNTHETIC RUBBER COMPANY LIMITED (JA) 1976-04-06 US claimed