Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20557346 | 1.00 | MAPT (0.51) | MAPTRAB9AALDH1A1NPC1THRB | |
| SCHEMBL27659630 | 0.85 | NFE2L2 (0.54) | MAPTRAB9AALDH1A1NPC1THRB | |
| SCHEMBL10373733 | 0.80 | ALDH1A1 (0.58) | MAPTRAB9AALDH1A1NPC1THRB | |
| SCHEMBL22347901 | 0.79 | PLK1 (0.57) | MAPTRAB9AALDH1A1NPC1THRB | |
| SCHEMBL7913090 | 0.79 | NPC1 (0.51) | MAPTRAB9AALDH1A1NPC1THRB | |
| SCHEMBL959834 | 0.78 | L3MBTL1 (0.52) | MAPTALDH1A1POLBSMN1; SMN2KMO | |
| SCHEMBL6435858 | 0.78 | SLC6A4 (0.54) | MAPTRAB9AALDH1A1NPC1THRB | |
| SCHEMBL22206166 | 0.77 | NPC1 (0.55) | MAPTRAB9AALDH1A1NPC1THRB | |
| SCHEMBL29838394 | 0.77 | NPC1 (0.55) | MAPTRAB9AALDH1A1NPC1THRB | |
| SCHEMBL20557352 | 0.77 | PDE4D (0.49) | MAPTRAB9AALDH1A1NPC1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283668-A | Diaryl ureas as CB1 allosteric modulators | 研究三角协会 | 2023-06-23 | — | — | CN | disclosed |