Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K9 | P80192 | 6/20 | 0.40 |
| ▸ | MAP3K11 | Q16584 | 6/20 | 0.40 |
| ▸ | PRKCA | P17252 | 5/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.39 |
| ▸ | PRKCG | P05129 | 3/20 | 0.39 |
| ▸ | PRKCB | P05771 | 3/20 | 0.39 |
| ▸ | PRKCH | P24723 | 3/20 | 0.39 |
| ▸ | PRKCI | P41743 | 3/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.39 |
| ▸ | PRKD1 | Q15139 | 3/20 | 0.39 |
| ▸ | GLI1 | P08151 | 2/20 | 0.39 |
| ▸ | GLI2 | P10070 | 2/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046598 | 0.76 | CDK4 (0.39) | PRKCAPRKCQPRKCDPRKD3PRKCG | |
| SCHEMBL3048043 | 0.73 | CCNB2 (0.35) | MAP3K9MAP3K11JAK3ROCK1CLK1 | |
| SCHEMBL3033775 | 0.66 | KDR (0.63) | MAP3K9MAP3K11PRKCAPRKCQPRKCD | |
| SCHEMBL13290543 | 0.65 | ALDH1A1 (0.51) | — | |
| SCHEMBL3042558 | 0.65 | NPC1 (0.52) | ROCK2PIM1ROCK1KDR | |
| SCHEMBL3053071 | 0.63 | ALDH1A1 (0.51) | PRKCAPRKCQPRKCDPRKCBPRKCH | |
| SCHEMBL3048710 | 0.62 | HSD17B10 (0.50) | PRKCAPRKCQPRKCDPRKCBPRKCH | |
| SCHEMBL30897563 | 0.61 | MEN1 (0.69) | MAP3K9MAP3K11PRKCAPRKCQPRKCD | |
| SCHEMBL13025156 | 0.60 | MAP3K11 (0.60) | MAP3K9MAP3K11PRKCAPRKCQPRKCD | |
| SCHEMBL23089702 | 0.60 | PIM1 (0.44) | MAP3K9MAP3K11PRKCAPRKCQPRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745641-B2 | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-06-29 | — | — | US | disclosed |
| US-20090054407-A1 | Nitrogen-containing heterocyclic compound | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1880993-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-01-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054407-A1 | Nitrogen-containing heterocyclic compound | NR4A1, NR5A2, PRMT8 | MAP3K9 3221/4885MAP3K11 3080/4885PRKCA 4487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.