SCHEMBL3047149

SCHEMBL3047149

Nc1ccccc1NCCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.53
HDAC6 Q9UBN7 1/20 0.53
ALDH1A1 P00352 3/20 0.52
LMNA P02545 3/20 0.52
CYP1A2 P05177 2/20 0.52
CYP2D6 P10635 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
RAB9A P51151 2/20 0.52
MAOA P21397 2/20 0.52
MAOB P27338 2/20 0.52
CYP3A4 P08684 2/20 0.52
NPC1 O15118 1/20 0.52
KDM1A O60341 1/20 0.52
HTR1A P08908 1/20 0.52
ADRA2A P08913 1/20 0.52
CYP2C8 P10632 1/20 0.52
IDO1 P14902 1/20 0.52
TSHR P16473 1/20 0.52
NFKB1 P19838 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7403954 0.89 HDAC6 (0.67) HDAC6MAOBHDAC1MEN1KMT2A
SCHEMBL19278371 0.85 TAAR1 (0.47) L3MBTL1HDAC6ALDH1A1ADRA1AHDAC1
SCHEMBL9193642 0.84 HDAC1 (0.54) L3MBTL1HDAC6ALDH1A1LMNAHDAC1
SCHEMBL17738673 0.83 L3MBTL1 (0.44) L3MBTL1HDAC6ALDH1A1LMNACYP1A2
SCHEMBL6201094 0.83 MAPT (0.52) L3MBTL1HDAC6ALDH1A1LMNACYP1A2
SCHEMBL28441434 0.82 HDAC6 (0.48) L3MBTL1HDAC6ALDH1A1LMNACYP1A2
SCHEMBL3999586 0.81 CHRNA7 (0.50) L3MBTL1CYP1A2CYP2D6RAB9ANPC1
SCHEMBL1519232 0.81 TAAR1 (0.54) HDAC6RAB9ANPC1IDO1TAAR1
SCHEMBL14007511 0.80 BACE1 (0.71) L3MBTL1ALDH1A1LMNARAB9ANPC1
SCHEMBL1470996 0.79 MEN1 (0.61) HDAC6ALDH1A1LMNACYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111032008-A Method for dyeing keratin materials using at least one blue, violet or green dye and at least one disulfide, thiol or protected thiol fluorescent dye 莱雅公司 2020-04-17 CN claimed
CN-111479485-A Hair dyeing kit and composition for use in hair dyeing kit 莱雅公司 2020-07-31 CN disclosed
CN-111094249-A P-phenylenediamine bases having cationic heterocycles and their use for the oxidation dyeing of keratin fibers 莱雅公司 2020-05-01 CN disclosed
CN-111094232-A P-phenylenediamine color bases F having an aliphatic chain and trialkylammonium groups and use thereof for oxidation dyeing of keratin fibers 莱雅公司 2020-05-01 CN disclosed
CN-107257797-B Use of azomethines bearing two pyrazolopyridine units for dyeing keratin fibres 欧莱雅 2020-04-17 CN disclosed
CN-104651476-B Novel nitroreductase substrates 生物梅里埃公司 2020-02-18 CN disclosed
EP-2479282-B1 Media including nitroreductase enzymatic substrates BIOMERIEUX SA (FR) 2018-03-28 EP disclosed
EP-2155893-B1 NOVEL NITROREDUCTASE ENZYMATIC SUBSTRATES BIOMERIEUX SA (FR) 2016-10-19 EP disclosed
EP-2471944-B1 Novel peptidase substrates BIOMERIEUX SA (FR) 2016-09-14 EP disclosed
EP-2155892-B1 NOVEL PEPTIDASE SUBSTRATES BIOMERIEUX SA (FR) 2015-03-18 EP disclosed
US-20030087928-A1 Novel anilide compounds and drugs containing the same KOWA COMPANY, LTD., JAPAN 2003-05-08 US disclosed
US-20020099074-A1 Novel anilide compounds and drugs containing the same KOWA COMPANY, LTD.,JAPAN 2002-07-25 US disclosed
US-6399629-B1 PYRROLIDINES AND PIPERIDINES FOR TREATING MICROBIAL INFECTIONS BY REDUCING EXPORT OF COADMINISTERED ANTIMICROBIAL AGENT OR COMPOUND SYNTHESIZED BY MICROBES FOR THEIR GROWTH; REDUCING IN VIVO AVAILABILITY MICROCIDE PHARMACEUTICALS, INC. 2002-06-04 US disclosed
US-6362208-B1 ANTICHOLESTEROL AGENT KOWA COMPANY, LTD. (JP) 2002-03-26 US disclosed
EP-1020451-A1 NOVEL ANILIDE COMPOUNDS AND DRUGS CONTAINING THE SAME Kowa Co., Ltd. (JP) 2000-07-19 EP disclosed
WO-2000001714-A1 EFFLUX PUMP INHIBITORS MICROCIDE PHARMACEUTICALS, INC. (US) 2000-01-13 WO disclosed
EP-0057870-B1 N-OPTIONELLY SUBSTITUTED-2-AMINO-ALPHA-PHENYLPHENETHYLAMINES AND A METHOD FOR THEIR PREPARATION HOECHST AKTIENGESELLSCHAFT (DE) 1985-07-31 EP disclosed
EP-0009800-B1 4-PHENYL-1,3-BENZODIAZEPINES, METHOD FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THE COMPOUNDS FOR USE AS MEDICAMENTS HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-23 EP disclosed
EP-0057870-A1 N-optionelly substituted-2-amino-alpha-phenylphenethylamines and a method for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1982-08-18 EP disclosed
EP-0009800-A2 4-Phenyl-1,3-benzodiazepines, method for their preparation, pharmaceutical compositions containing them, and the compounds for use as medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1980-04-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087928-A1 Novel anilide compounds and drugs containing the same ACAT1, ACAT2, LCAT L3MBTL1 4152/4885HDAC6 55/4885ALDH1A1 211/4885
US-20020099074-A1 Novel anilide compounds and drugs containing the same SOAT1, SOAT2, LCAT L3MBTL1 3419/4885HDAC6 92/4885ALDH1A1 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.