SCHEMBL30471908

SCHEMBL30471908

[Ir+3].c1ccc(-c2ccc(-c3ccccc3)nc2)cc1.c1ccc(-c2ccc(-c3ccccc3)nc2)cc1.c1ccc(-c2ccc(-c3ccccc3)nc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGDS O60760 1/20 0.56
LDHA P00338 1/20 0.53
HSD17B1 P14061 1/20 0.52
HSD17B2 P37059 1/20 0.52
NPC1 O15118 2/20 0.50
NFKB1 P19838 2/20 0.50
RAB9A P51151 2/20 0.50
NFKB2 Q00653 2/20 0.50
RELA Q04206 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CYP11B1 P15538 5/20 0.47
CYP11B2 P19099 5/20 0.47
BAZ2B Q9UIF8 1/20 0.46
CHRNB2 P17787 1/20 0.45
CHRNA3 P32297 1/20 0.45
GABRA1 P14867 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25118611 0.98 HPGDS (0.58) HPGDSLDHAHSD17B1HSD17B2NPC1
SCHEMBL903715 0.98 HPGDS (0.58) HPGDSLDHAHSD17B1HSD17B2NPC1
SCHEMBL12523550 0.98 HPGDS (0.58) HPGDSLDHAHSD17B1HSD17B2NPC1
SCHEMBL913315 0.98 HPGDS (0.58) HPGDSLDHAHSD17B1HSD17B2NPC1
SCHEMBL29578423 0.98 HPGDS (0.58) HPGDSLDHAHSD17B1HSD17B2NPC1
SCHEMBL500158 0.95 HPGDS (0.56) HPGDSLDHAHSD17B1HSD17B2NPC1
Iodide SCHEMBL30978328 0.95 HPGDS (0.56) HPGDSLDHAHSD17B1HSD17B2NPC1
SCHEMBL12973036 0.95 HPGDS (0.60) HPGDSLDHAHSD17B1HSD17B2NPC1
SCHEMBL3146845 0.90 NPC1 (0.54) HPGDSLDHAHSD17B1HSD17B2NPC1
SCHEMBL13910992 0.88 HSD17B1 (0.55) HPGDSLDHAHSD17B1HSD17B2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12082493-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-09-03 US disclosed
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-11690286-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12082493-B2 Organic electroluminescent materials and devices NONO, ORC3, TYR HPGDS 4043/4885LDHA 906/4885HSD17B1 3770/4885
US-20230320196-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NONO, ORC3, TYR HPGDS 4043/4885LDHA 906/4885HSD17B1 3770/4885
US-11690286-B2 Organic electroluminescent materials and devices NONO, ORC3, LEF1 HPGDS 3789/4885LDHA 669/4885HSD17B1 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.