Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25886931 | 1.00 | KDM4E (0.30) | KDM4EHSD17B10 | |
| SCHEMBL25886440 | 0.92 | KDM4E (0.31) | KDM4EHSD17B10 | |
| SCHEMBL17688763 | 0.92 | PTGS2 (0.32) | KDM4EHSD17B10 | |
| SCHEMBL31003482 | 0.86 | EGLN1 (0.35) | — | |
| SCHEMBL22685141 | 0.86 | DDR1 (0.31) | — | |
| SCHEMBL31003490 | 0.86 | DDR1 (0.31) | — | |
| SCHEMBL25427707 | 0.85 | POLB (0.37) | KDM4EHSD17B10 | |
| SCHEMBL31081529 | 0.85 | POLB (0.37) | KDM4EHSD17B10 | |
| SCHEMBL31003480 | 0.85 | — | — | |
| SCHEMBL31081310 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435083-B2 | Cyclopropyl-(hetero)aryl-substituted ethylsulphonyl-pyridine derivatives | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2025-10-07 | — | — | US | disclosed |
| US-20240300957-A1 | TETRAZOLE-SUBSTITUTED ETHYL-SULFONE / SULFOXIMINE-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-09-12 | — | — | US | disclosed |
| WO-2024175558-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYL-SULFONE/SULFOXIMINE-PYRIDINE N-OXIDE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-08-29 | — | — | WO | disclosed |
| WO-2024175559-A1 | TETRAZOLE-SUBSTITUTED ETHYL-SULFONE/SULFOXIMINE-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-08-29 | — | — | WO | disclosed |
| US-20230234951-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234951-A1 | CYCLOPROPYL-(HETERO)ARYL-SUBSTITUTED ETHYLSULPHONYL-PYRIDINE DERIVATIVES | CYCS, CYP2E1, AHR | KDM4E 930/4885HSD17B10 2581/4885 |
| US-20240300957-A1 | TETRAZOLE-SUBSTITUTED ETHYL-SULFONE / SULFOXIMINE-PYRIDINE DERIVATIVES | TST, STS, SQOR | KDM4E 1155/4885HSD17B10 3651/4885 |
| US-12435083-B2 | Cyclopropyl-(hetero)aryl-substituted ethylsulphonyl-pyridine derivatives | CYCS, CYP2E1, CYP1A1 | KDM4E 1000/4885HSD17B10 2429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.