Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
| ▸ | TNKS | O95271 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25035187 | 0.84 | PDE3B (0.41) | CRBNTNKSPARP1TNKS2PARP10 | |
| SCHEMBL30135802 | 0.84 | PDE3B (0.41) | CRBNTNKSPARP1TNKS2PARP10 | |
| SCHEMBL30475454 | 0.82 | ALDH1A1 (0.42) | CRBNTNKSPARP1TNKS2PARP10 | |
| SCHEMBL25035194 | 0.82 | ALDH1A1 (0.42) | CRBNTNKSPARP1TNKS2PARP10 | |
| SCHEMBL25033928 | 0.78 | PDE3B (0.41) | CRBNTNKSPARP1TNKS2PARP10 | |
| SCHEMBL25035191 | 0.77 | PLK1 (0.68) | — | |
| SCHEMBL25033922 | 0.76 | ALDH1A1 (0.42) | CRBNTNKSPARP1TNKS2PARP10 | |
| SCHEMBL30475449 | 0.76 | DRD2 (0.46) | CRBNPDE3BPDE3A | |
| SCHEMBL25035190 | 0.76 | DRD2 (0.46) | CRBNPDE3BPDE3A | |
| SCHEMBL31255446 | 0.70 | SMYD3 (0.50) | CRBNALDH1A1LMNAKMT2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116322700-B | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-08-20 | — | — | CN | disclosed |
| CN-116322700-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-23 | — | — | CN | disclosed |