Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.39 |
| ▸ | DRD3 | P35462 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30475454 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KMT2AHPGDMEN1LMNA | |
| SCHEMBL25033922 | 0.93 | ALDH1A1 (0.42) | ALDH1A1KMT2AHPGDMEN1LMNA | |
| SCHEMBL25035187 | 0.84 | PDE3B (0.41) | ALDH1A1KMT2AHPGDMEN1LMNA | |
| SCHEMBL30135802 | 0.84 | PDE3B (0.41) | ALDH1A1KMT2AHPGDMEN1LMNA | |
| SCHEMBL25035190 | 0.84 | DRD2 (0.46) | CRBNDDB1PDE3BPDE3AP2RY12 | |
| SCHEMBL30475449 | 0.84 | DRD2 (0.46) | CRBNDDB1PDE3BPDE3AP2RY12 | |
| SCHEMBL25824324 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KMT2AHPGDMEN1LMNA | |
| SCHEMBL30475465 | 0.82 | CRBN (0.41) | ALDH1A1KMT2AHPGDMEN1LMNA | |
| SCHEMBL25034750 | 0.80 | HTR7 (0.44) | ALDH1A1TNKSPARP1PARP10TNKS2 | |
| SCHEMBL30475475 | 0.80 | HTR7 (0.44) | ALDH1A1TNKSPARP1PARP10TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018238-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |
| WO-2023017446-A1 | NOVEL PLK1 DEGRADATION INDUCING COMPOUND | UPPTHERA, INC. (KR) | 2023-02-16 | — | — | WO | disclosed |