Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25824951 | 1.00 | GRM5 (0.41) | GRM5SQORL3MBTL1LMNACYP1A2 | |
| SCHEMBL25819527 | 0.85 | L3MBTL1 (0.43) | GRM5SQORL3MBTL1LMNACYP1A2 | |
| SCHEMBL19586404 | 0.83 | ALDH1A1 (0.43) | GRM5SQORL3MBTL1LMNATRPV3 | |
| SCHEMBL29170223 | 0.82 | GRM5 (0.44) | GRM5SQORL3MBTL1LMNACYP1A2 | |
| SCHEMBL21055273 | 0.79 | LMNA (0.48) | GRM5L3MBTL1LMNACYP1A2PTGS1 | |
| SCHEMBL24207230 | 0.79 | LMNA (0.47) | GRM5SQORL3MBTL1LMNACYP1A2 | |
| SCHEMBL31390651 | 0.79 | LMNA (0.44) | GRM5SQORL3MBTL1LMNACYP1A2 | |
| SCHEMBL19585970 | 0.78 | GRM5 (0.41) | GRM5SQORL3MBTL1LMNACYP1A2 | |
| SCHEMBL30475462 | 0.78 | SQOR (0.44) | GRM5SQORL3MBTL1TRPV3MAPK1 | |
| SCHEMBL25035127 | 0.78 | SQOR (0.44) | GRM5SQORL3MBTL1TRPV3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116322700-B | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2024-08-20 | — | — | CN | disclosed |
| CN-116322700-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-23 | — | — | CN | disclosed |