Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25033869 | 1.00 | TRPV3 (0.37) | TRPV3LTB4RL3MBTL1MCL1BAK1 | |
| SCHEMBL25819525 | 0.92 | CCNT1 (0.34) | TRPV3LTB4RL3MBTL1CCNT1P2RY12 | |
| SCHEMBL25033937 | 0.84 | FFAR4 (0.40) | TRPV3MCL1BAK1 | |
| SCHEMBL25821509 | 0.84 | FFAR4 (0.43) | LTB4RMCL1BAK1 | |
| SCHEMBL26641260 | 0.79 | FFAR4 (0.39) | LTB4RMCL1BAK1 | |
| SCHEMBL19586404 | 0.77 | ALDH1A1 (0.43) | TRPV3L3MBTL1GRM5 | |
| SCHEMBL24881105 | 0.76 | PRMT5 (0.36) | TRPV3CCNT1 | |
| SCHEMBL24670625 | 0.75 | GPR119 (0.51) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL29990087 | 0.75 | GPR119 (0.51) | CCNT1CCNA2CDK2CDK9CCNA1 | |
| SCHEMBL27411319 | 0.75 | PTPN1 (0.47) | MCL1BAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116322700-A | Novel PLK1 degradation inducing compounds | 厄普特拉株式会社 | 2023-06-23 | — | — | CN | disclosed |