Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2618803 | 0.81 | TDP1 (0.55) | KDM4CKDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL30298673 | 0.81 | TDP1 (0.55) | KDM4CKDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL25201864 | 0.77 | KDM4C (0.42) | KDM4CKDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL17425264 | 0.75 | LOXL2 (0.41) | KDM4CKDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL82604 | 0.75 | KDM4C (0.59) | KDM4CKDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL29578794 | 0.75 | KDM4C (0.59) | KDM4CKDM4ETDP1ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1027857 | 0.73 | KDM4C (0.57) | KDM4CKDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL724581 | 0.73 | ALDH1A1 (0.52) | KDM4CKDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL19273667 | 0.73 | LOXL2 (0.39) | KDM4CKDM4ETDP1ALDH1A1L3MBTL1 | |
| SCHEMBL459712 | 0.73 | LOXL2 (0.44) | KDM4CKDM4ETDP1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110183422-B | Nuclear transport modulators and uses thereof | 卡尔约药物治疗公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-110386919-B | Nuclear transport modulators and uses thereof | 卡尔约药物治疗公司 | 2023-07-14 | — | — | CN | disclosed |