Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22041563 | 1.00 | CRHBP (0.48) | CRHBPCRHR2HRH3PIK3CDPIK3CA | |
| SCHEMBL16597162 | 0.85 | HSP90AB1 (0.49) | PIK3CDMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL16597163 | 0.80 | CRHBP (0.45) | CRHBPCRHR2HRH3PIK3CDPIK3CG | |
| SCHEMBL30475817 | 0.78 | PIK3CD (0.47) | HRH3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL22041485 | 0.78 | PIK3CD (0.47) | HRH3PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL22238025 | 0.78 | HTR3A (0.36) | CRHBPCRHR2HRH3PIK3CDMEN1 | |
| SCHEMBL16596949 | 0.78 | GAA (0.53) | CRHBPCRHR2HRH3PIK3CDPIK3CA | |
| SCHEMBL21185376 | 0.77 | CRHBP (0.43) | CRHBPCRHR2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL22519319 | 0.76 | PIK3CD (0.56) | CRHBPCRHR2PIK3CD | |
| SCHEMBL12264013 | 0.76 | CYP11B2 (0.52) | MEN1LMNAKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111269231-B | Selective PI3K delta inhibitor and application thereof | 安徽中科拓苒药物科学研究有限公司 | 2023-06-09 | — | — | CN | disclosed |