SCHEMBL30477002

SCHEMBL30477002

Clc1nc(-c2ccc3ccccc3c2)nc(-c2cccc3oc4ccccc4c23)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.37
ALDH1A1 P00352 5/20 0.37
CYP1A2 P05177 4/20 0.37
HSD17B10 Q99714 4/20 0.37
KDM4E B2RXH2 3/20 0.37
CYP2C19 P33261 2/20 0.37
RAB9A P51151 2/20 0.37
ATM Q13315 1/20 0.37
AHR P35869 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PIM1 P11309 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
TP53 P04637 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALOX5 P09917 1/20 0.34
MAPT P10636 2/20 0.34
PRKDC P78527 1/20 0.34
CYP2C9 P11712 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23753687 1.00 BACE1 (0.37) BACE1ALDH1A1CYP1A2HSD17B10KDM4E
SCHEMBL25818489 0.96 BACE1 (0.36) BACE1ALDH1A1CYP1A2HSD17B10KDM4E
SCHEMBL22274543 0.96 BACE1 (0.36) BACE1ALDH1A1CYP1A2HSD17B10KDM4E
SCHEMBL25506465 0.96 BACE1 (0.36) BACE1ALDH1A1CYP1A2HSD17B10KDM4E
SCHEMBL21709042 0.93 TDP1 (0.39) BACE1ALDH1A1CYP1A2HSD17B10KDM4E
SCHEMBL21148485 0.93 TDP1 (0.39) BACE1ALDH1A1CYP1A2HSD17B10KDM4E
SCHEMBL25506707 0.93 HCRTR1 (0.34) BACE1ALDH1A1CYP1A2HSD17B10KDM4E
SCHEMBL23819720 0.93 PIM1 (0.36) BACE1ALDH1A1CYP1A2HSD17B10KDM4E
SCHEMBL26260468 0.92 HSD17B1 (0.38) ALDH1A1CYP1A2HSD17B10KDM4ECYP2C19
SCHEMBL25818422 0.91 PLA2G2A (0.38) BACE1ALDH1A1CYP1A2HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119569709-A Organic electroluminescent compound, various host materials, and organic electroluminescent device comprising the same 杜邦特种材料韩国有限公司 2025-03-07 CN disclosed
CN-119330945-A Organic compound, organic electroluminescent material and application thereof 北京鼎材科技有限公司 2025-01-21 CN disclosed
CN-118772137-A Multiple host materials, organic electroluminescent compounds, and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2024-10-15 CN disclosed
US-20240276872-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-08-15 US disclosed
CN-118344281-A Multiple host materials and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2024-07-16 CN disclosed
CN-117886770-A Organic electroluminescent compound, various host materials, and organic electroluminescent device comprising the same 罗门哈斯电子材料韩国有限公司 2024-04-16 CN disclosed
CN-116425762-A Organic electroluminescent compound and organic electroluminescent device 北京云基科技股份有限公司 2023-07-14 CN disclosed
CN-116425724-A Organic electroluminescent compound and organic electroluminescent device 北京云基科技股份有限公司 2023-07-14 CN disclosed
CN-116396300-A Organic electroluminescent compound and organic electroluminescent device 北京云基科技股份有限公司 2023-07-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240276872-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LIMS1, PIEZO1, LGALS4 BACE1 2919/4885ALDH1A1 912/4885CYP1A2 3635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.