Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.46 |
| ▸ | ITGA2 | P17301 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 10/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25331253 | 1.00 | ITGB3 (0.46) | ITGB3ITGA2BITGA2CASP3CASP7 | |
| SCHEMBL25330768 | 0.91 | SDCBP (0.45) | ITGB3ITGA2BITGA2CASP3CASP7 | |
| SCHEMBL30477277 | 0.91 | SDCBP (0.45) | ITGB3ITGA2BITGA2CASP3CASP7 | |
| SCHEMBL25330777 | 0.91 | SDCBP (0.45) | ITGB3ITGA2BITGA2CASP3CASP7 | |
| SCHEMBL25331801 | 0.89 | ITGB3 (0.42) | ITGB3ITGA2BITGA2CASP3CASP7 | |
| SCHEMBL30477318 | 0.89 | ITGB3 (0.42) | ITGB3ITGA2BITGA2CASP3CASP7 | |
| SCHEMBL25330547 | 0.83 | CASP1 (0.39) | ITGB3ITGA2BITGA2CASP3CASP7 | |
| SCHEMBL25330532 | 0.83 | CASP1 (0.39) | ITGB3ITGA2BITGA2CASP3CASP7 | |
| SCHEMBL311763 | 0.83 | THRB (0.52) | CASP3CASP7CASP9CASP6CASP8 | |
| SCHEMBL31155725 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2BITGA2CASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118510754-A | Novel isoindolinone derivative compounds as caspase inhibitors | 因诺沃治疗有限公司 | 2024-08-16 | — | — | CN | claimed |
| CN-118510754-A | Novel isoindolinone derivative compounds as caspase inhibitors | 因诺沃治疗有限公司 | 2024-08-16 | — | — | CN | disclosed |
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |