SCHEMBL304777

SCHEMBL304777

[CH2]CC1CC(C)CC(C)C1

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL910589 0.97
SCHEMBL5388249 0.77
SCHEMBL11904024 0.77 EPHX2 (0.34) EPHX2
SCHEMBL16191189 0.73 EPHX2 (0.40) EPHX2
SCHEMBL10587945 0.73 EPHX2 (0.40) EPHX2
SCHEMBL6585501 0.73 ACHE (0.35)
SCHEMBL5334995 0.73
SCHEMBL7887727 0.71 EPHX2 (0.39) EPHX2
SCHEMBL6592107 0.71 ACHE (0.39)
SCHEMBL23420992 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11332779-B2 Nucleic acid melting analysis with saturation dyes BIOFIRE DEFENSE, LLC (US) 2022-05-17 US disclosed
US-20200248247-A1 Nucleic Acid Melting Analysis with Saturation Dyes UNIVERSITY OF UTAH 2020-08-06 US disclosed
EP-2826867-B1 Nucleic acid melting analysis with saturation dyes UNIV UTAH RES FOUND (US) 2020-06-03 EP disclosed
US-10655169-B2 Nucleic acid melting analysis with saturation dyes UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2020-05-19 US disclosed
EP-2772552-B1 Amplicon melting analysis with saturation dyes UNIV UTAH RES FOUND (US) 2018-10-10 EP disclosed
US-20180066137-A1 AMPLICON MELTING ANALYSIS WITH SATURATION DYES WITTWER CARL T (US) 2018-03-08 US disclosed
US-9850381-B2 Amplicon melting analysis with saturation dyes UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2017-12-26 US disclosed
US-20170226573-A1 NUCLEIC ACID MELTING ANALYSIS WITH SATURATION DYES UNIVERSITY OF UTAH 2017-08-10 US disclosed
US-9657347-B2 Nucleic acid melting analysis with saturation dyes University of Utah Research Foundation and BioFire Defense, LLC (US) 2017-05-23 US disclosed
US-9290663-B2 Amplicon melting analysis with saturation dyes UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2016-03-22 US disclosed
US-7387887-B2 Nucleic acid melting analysis with saturation dyes UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2008-06-17 US disclosed
CN-101198706-A Nucleic acid melting analysis with saturating dyes UNIV UTAH RES FOUND (US) 2008-06-11 CN disclosed
EP-1774047-A2 NUCLEIC ACID MELTING ANALYSIS WITH SATURATION DYES University of Utah Research Foundation (US) 2007-04-18 EP disclosed
CN-1934270-A Amplicon melting analysis with saturation dyes UNIV UTAH RES FOUND (US) 2007-03-21 CN disclosed
US-20070020672-A1 Nucleic acid melting analysis with saturation dyes IDAHO TECHNOLOGY, INC. (US) 2007-01-25 US disclosed
WO-2006121423-A2 NUCLEIC ACID MELTING ANALYSIS WITH SATURATION DYES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2006-11-16 WO disclosed
US-20060019253-A1 Polymerase chain reaction analysis by mixing a dsDNA binding dye with a sample of target nucleic acid and primers configured for amplifying; melting the amplified target nucleic acid to generate a melting curve; plotting; repeating; comparison; melting curve difference for each target nucleic acid NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-01-26 US disclosed
US-20050233335-A1 standard PCR solution with additional saturating double-stranded (ds) DNA binding dye; fluorescence; cyanine dyes UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2005-10-20 US disclosed
EP-1558762-A2 AMPLICON MELTING ANALYSIS WITH SATURATION DYES University of Utah Research Foundation (US) 2005-08-03 EP disclosed
WO-2004038038-A2 AMPLICON MELTING ANALYSIS WITH SATURATION DYES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2004-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060019253-A1 Polymerase chain reaction analysis by mixing a dsDNA binding dye with a sample of target nucleic acid and primers configured for amplifying; melting the amplified target nucleic acid to generate a melting curve; plotting; repeating; comparison; melting curve difference for each target nucleic acid POLL, DNA2, POLRMT EPHX2 3758/4885
US-20070020672-A1 Nucleic acid melting analysis with saturation dyes DNA2, POLL, POLRMT EPHX2 4323/4885
US-20050233335-A1 standard PCR solution with additional saturating double-stranded (ds) DNA binding dye; fluorescence; cyanine dyes DDB1, POLL, POLRMT EPHX2 4833/4885
US-20180066137-A1 AMPLICON MELTING ANALYSIS WITH SATURATION DYES NOP2, POLL, DNA2 EPHX2 3390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.