Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 10/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28897988 | 1.00 | TDP2 (0.43) | TDP2PARP10PARP11TYRO3NTRK2 | |
| SCHEMBL28451556 | 0.82 | ALDH1A1 (0.41) | PARP10PARP11MEN1LMNAMAPT | |
| SCHEMBL30477977 | 0.82 | ALDH1A1 (0.41) | PARP10PARP11MEN1LMNAMAPT | |
| SCHEMBL30477992 | 0.81 | MAOA (0.37) | TDP2MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL28456875 | 0.81 | MAOA (0.37) | TDP2MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL28897519 | 0.81 | HSP90AA1 (0.39) | NPC1MAPTHTTRAB9ASMN1; SMN2 | |
| SCHEMBL30477983 | 0.81 | METAP1 (0.39) | TDP2PARP10PARP11LMNAMAPT | |
| SCHEMBL28453681 | 0.81 | METAP1 (0.39) | TDP2PARP10PARP11LMNAMAPT | |
| SCHEMBL30477985 | 0.81 | PARP1 (0.35) | ACHE | |
| SCHEMBL30477987 | 0.81 | HSP90AA1 (0.39) | NPC1MAPTHTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533764-B | Method for preparing siloxyindene derivative by utilizing domino reaction | 杭州师范大学 | 2023-06-06 | — | — | CN | disclosed |