Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28456875 | 1.00 | MAOA (0.37) | MAOAMAOBBCHECES1KDM4E | |
| SCHEMBL30477982 | 0.84 | MAOA (0.33) | MAOAMAOBBCHECES1KDM4E | |
| SCHEMBL28447657 | 0.84 | MAOA (0.33) | MAOAMAOBBCHECES1KDM4E | |
| SCHEMBL30477989 | 0.84 | MAOA (0.33) | MAOAMAOBBCHECES1KDM4E | |
| SCHEMBL28449321 | 0.84 | MAOA (0.33) | MAOAMAOBBCHECES1KDM4E | |
| SCHEMBL28451137 | 0.83 | GABRP (0.36) | MAOAMAOBBCHECES1KDM4E | |
| SCHEMBL30477990 | 0.83 | GABRP (0.36) | MAOAMAOBBCHECES1KDM4E | |
| SCHEMBL28451395 | 0.81 | METAP1 (0.40) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28449271 | 0.81 | MEN1 (0.32) | MAOBKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28451556 | 0.81 | ALDH1A1 (0.41) | MAOAMAOBKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111533764-B | Method for preparing siloxyindene derivative by utilizing domino reaction | 杭州师范大学 | 2023-06-06 | — | — | CN | disclosed |