SCHEMBL825205

SCHEMBL825205

C#CCOc1ccc(C=O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.54
MAOB P27338 3/20 0.54
PTGS2 P35354 2/20 0.54
CA12 O43570 3/20 0.53
CA9 Q16790 3/20 0.53
CA2 P00918 2/20 0.53
CA1 P00915 2/20 0.53
CA4 P22748 2/20 0.53
GSTP1 P09211 1/20 0.53
CA7 P43166 1/20 0.53
ALDH1A1 P00352 6/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 1/20 0.47
HPGD P15428 1/20 0.47
CYP2A6 P11509 1/20 0.47
KDM4E B2RXH2 4/20 0.45
HDAC3 O15379 2/20 0.45
HDAC2 Q92769 2/20 0.45
HDAC8 Q9BY41 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20305460 0.88 CYP19A1 (0.54) MAOAMAOBPTGS2CA12CA9
SCHEMBL20305350 0.87 PTGS2 (0.45) MAOAMAOBPTGS2CA12CA9
SCHEMBL23315105 0.84 CA12 (0.54) MAOAMAOBPTGS2CA12CA9
SCHEMBL10690394 0.83 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2LMNAMAPTHPGD
SCHEMBL31286481 0.83 ALDH1A1 (0.47) MAOAMAOBPTGS2CA12CA9
SCHEMBL16585081 0.83 ALDH1A1 (0.51) MAOAMAOBPTGS2CA12CA9
SCHEMBL19952676 0.83 ALDH1A1 (0.47) MAOAMAOBPTGS2CA12CA9
SCHEMBL5704167 0.82 CA12 (0.63) MAOAMAOBPTGS2CA12CA9
SCHEMBL31233273 0.82 MAOB (0.49) MAOAMAOBPTGS2CA12CA9
SCHEMBL8011907 0.82 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2LMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 204 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504863-A Phosphaphenanthrene-containing compound, epoxy resin material, and preparation methods and applications thereof 岭南师范学院 2025-02-25 CN claimed
CN-116004030-B Azamethylenedipyrrole metal complex dye based on click chemistry, and preparation method and application thereof 天津大学 2024-08-16 CN claimed
CN-116004030-A Azamethylenedipyrrole metal complex dye based on click chemistry, and preparation method and application thereof 天津大学 2023-04-25 CN claimed
WO-2014073003-A1 SINGLE-STEP PROCESS FOR THE PREPARATION OF ARYL OLEFINS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-05-15 WO claimed
US-12584023-B2 Composition for forming organic film, patterning process, and compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-03-24 US disclosed
EP-4239408-B1 COMPOSITION FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND SHINETSU CHEMICAL CO (JP) 2025-12-10 EP disclosed
US-20250354195-A1 METHOD OF SCREENING UNIV DUNDEE (GB) 2025-11-20 US disclosed
EP-3759075-B1 COMPOUNDS WITH FERROPTOSIS INDUCING ACTIVITY AND METHODS OF THEIR USE FERRO THERAPEUTICS INC (US) 2025-07-23 EP disclosed
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) 2025-06-12 US disclosed
US-20250129101-A1 Compound, Pharmaceutical Composition Comprising the Same and Method for Treating Cancer Using the Same NATIONAL TSING HUA UNIVERSITY (TW) 2025-04-24 US disclosed
CN-119504863-A Phosphaphenanthrene-containing compound, epoxy resin material, and preparation methods and applications thereof 岭南师范学院 2025-02-25 CN disclosed
US-20250011330-A1 Imidazo[1,2- a]pyrazine and Imidazo[1,2- a]pyridine Based Tyrosyl-DNA Phosphodiesterase I (TDP1) Inhibitors LEIDOS BIOMEDICAL RESEARCH INC. 2025-01-09 US disclosed
US-4654344-A ALSO AFFECT BLOOD PRESSURE AND MYOCARDIAL CONTRACTIONS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1987-03-31 US disclosed
EP-0093951-B1 2-ARYL-TETRAAZAINDENES MERCK PATENT GmbH (DE) 1986-10-29 EP disclosed
US-4616090-A 2-arylimidazopyridines intermediates MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-10-07 US disclosed
EP-0072926-B1 2-ARYLIMIDAZOPYRIDINES MERCK PATENT GmbH (DE) 1986-09-24 EP disclosed
US-4575505-A Pharmaceutical compositions containing 2-aryltetraazaindenes for treating ulcers or cardiac insufficiency or blood pressure abnormalities MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-03-11 US disclosed
US-4477454-A INDOTROPIC AGENTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1984-10-16 US disclosed
EP-0093951-A2 2-Aryl-tetraazaindenes MERCK PATENT GmbH (DE) 1983-11-16 EP disclosed
EP-0072926-A1 2-Arylimidazopyridines MERCK PATENT GmbH (DE) 1983-03-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188110-A1 SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION KMT5A, KMT5B, KMT5C MAOA 1069/4885MAOB 648/4885PTGS2 4339/4885
US-20250129101-A1 Compound, Pharmaceutical Composition Comprising the Same and Method for Treating Cancer Using the Same RB1, TP53, ASH2L MAOA 3440/4885MAOB 2756/4885PTGS2 2070/4885
US-20250011330-A1 Imidazo[1,2- a]pyrazine and Imidazo[1,2- a]pyridine Based Tyrosyl-DNA Phosphodiesterase I (TDP1) Inhibitors TDP1, TDP2, TOP1 MAOA 1115/4885MAOB 1589/4885PTGS2 2281/4885
US-12584023-B2 Composition for forming organic film, patterning process, and compound F12, MLX, F11 MAOA 2691/4885MAOB 3131/4885PTGS2 1935/4885
US-20250354195-A1 METHOD OF SCREENING PAICS, COASY, ABCG2 MAOA 63/4885MAOB 27/4885PTGS2 3104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.