SCHEMBL3048258

SCHEMBL3048258

CCCN(CCO)C(=O)Nc1ccc(N2CCN(c3ccc(OC)cc3)CC2)cc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.56
MEN1 O00255 3/20 0.56
RAB9A P51151 2/20 0.56
NPC1 O15118 1/20 0.56
GFER P55789 1/20 0.54
REV1 Q9UBZ9 1/20 0.54
MAPT P10636 7/20 0.52
ALDH1A1 P00352 1/20 0.52
NR4A1 P22736 1/20 0.52
MCL1 Q07820 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.50
LMNA P02545 2/20 0.50
RXFP1 Q9HBX9 1/20 0.50
SLC1A2 P43004 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
TP53 P04637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13137657 0.83 KMT2A (0.55) KMT2AMEN1RAB9ANPC1GFER
SCHEMBL10498609 0.77 LMNA (0.51) KMT2AMEN1RAB9ANPC1GFER
SCHEMBL15928331 0.77 NPY5R (0.61) KMT2AMEN1RAB9ANPC1GFER
SCHEMBL19173201 0.76 RXFP1 (0.72) KMT2AMEN1RAB9ANPC1GFER
SCHEMBL11089709 0.76 LMNA (0.49) KMT2AMEN1RAB9ANPC1GFER
SCHEMBL7454467 0.76 KMT2A (0.72) KMT2AMEN1RAB9ANPC1GFER
SCHEMBL15800700 0.76 KMT2A (0.72) KMT2AMEN1RAB9ANPC1GFER
SCHEMBL13900720 0.75 NPC1 (0.47) KMT2AMEN1RAB9ANPC1MAPT
SCHEMBL9435378 0.75 CNR1 (0.56) KMT2AMEN1RAB9ANPC1MAPT
Hydrochloric Acid SCHEMBL9038264 0.74 KMT2A (0.70) KMT2AMEN1RAB9ANPC1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130237705-A1 METHOD FOR MANUFACTURE OF 2-OXOIMIDAZOLIDINES PETERSON JOHN R (US) 2013-09-12 US disclosed
US-8431699-B2 Method for manufacture of 2-oxoimidazolidines Vertichem Corporation (CA) 2013-04-30 US disclosed
US-20100222588-A1 Method for Manufacture of 2-Oxoimidazolidines THESIS CHEMISTRY, LLC (US) 2010-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130237705-A1 METHOD FOR MANUFACTURE OF 2-OXOIMIDAZOLIDINES ODC1, NISCH, IMPDH2 KMT2A 2171/4885MEN1 1188/4885RAB9A 3064/4885
US-20100222588-A1 Method for Manufacture of 2-Oxoimidazolidines ODC1, CBR3, CBR1 KMT2A 1520/4885MEN1 1630/4885RAB9A 3458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.