Neurotensin

Neurotensin

SCHEMBL30483709

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCC(=O)N1)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 2/20 0.61
▸ NPY2R P49146 7/20 0.58
▸ NPY4R P50391 7/20 0.58
▸ NPY5R Q15761 7/20 0.58
▸ NPY1R P25929 6/20 0.58
▸ NTSR1 P30989 5/20 0.58
▸ NTSR2 O95665 3/20 0.58
▸ MAPK8 P45983 1/20 0.58
▸ MAPK9 P45984 1/20 0.58
▸ MAPK10 P53779 1/20 0.58
▸ SORT1 Q99523 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30957024 1.00 KDM1A (0.61) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL38650581 0.95 KDM1A (0.62) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL31302260 0.94 KDM1A (0.58) KDM1ANPY2RNPY4RNPY5RNPY1R
Neurotensin SCHEMBL29851748 0.92 NTSR1 (0.70) NPY1RNTSR1NTSR2SORT1
Neurotensin SCHEMBL29357707 0.92 NTSR1 (0.70) NPY1RNTSR1NTSR2SORT1
SCHEMBL31548697 0.92 NTSR1 (0.66) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL31738531 0.92 NTSR1 (0.66) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL29368585 0.90 NTSR1 (0.63) KDM1ANPY2RNPY4RNPY5RNPY1R
SCHEMBL30102522 0.90 NTSR1 (0.70) NPY2RNPY4RNPY5RNPY1RNTSR1
SCHEMBL20808279 0.88 KDM1A (0.61) KDM1ANPY2RNPY4RNPY5RNPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137818-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF NUCLIDIUM AG (CH) 2026-05-21 — — US disclosed
US-12527885-B2 High purity copper radiopharmaceutical compositions and diagnostic and therapeutic uses thereof NUCLIDIUM AG (CH) 2026-01-20 — — US disclosed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 — — EP disclosed
EP-4551251-A2 CNS TARGETING COMPLEXES AND USES THEREOF Dyne Therapeutics, Inc. (US) 2025-05-14 — — EP disclosed
CN-119790075-A CNS targeting complexes and uses thereof 达因疗法公司 2025-04-08 — — CN disclosed
WO-2024239281-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2024-11-28 — — WO disclosed
CN-118234736-A Method for producing peptide, method for removing protecting group, remover, and benzyl compound 株式会社德山 2024-06-21 — — CN disclosed
US-20240189460-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF NUCLIDIUM AG (CH) 2024-06-13 — — US disclosed
US-20240173440-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF NUCLIDIUM AG (CH) 2024-05-30 — — US disclosed
US-20240173441-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF NUCLIDIUM AG (CH) 2024-05-30 — — US disclosed
WO-2024011150-A2 CNS TARGETING COMPLEXES AND USES THEREOF DYNE THERAPEUTICS, INC. (US) 2024-01-11 — — WO disclosed
WO-2023127331-A1 PEPTIDE PRODUCTION METHOD, PROTECTING GROUP REMOVING METHOD, REMOVING AGENT, AND BENZYL COMPOUND 株式会社トクヤマ 2023-07-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527885-B2 High purity copper radiopharmaceutical compositions and diagnostic and therapeutic uses thereof SSTR1, PSMA1, KLK3 KDM1A 1551/4885NPY2R 198/4885NPY4R 744/4885
US-20240173441-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF SSTR1, SSTR3, SSTR2 KDM1A 4286/4885NPY2R 48/4885NPY4R 77/4885
US-20260137818-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF FAP, SSTR1, PSMA1 KDM1A 2015/4885NPY2R 249/4885NPY4R 613/4885
US-20240173440-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF SSTR1, SSTR3, SSTR2 KDM1A 4286/4885NPY2R 48/4885NPY4R 77/4885
US-20240189460-A1 HIGH PURITY COPPER RADIOPHARMACEUTICAL COMPOSITIONS AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF SSTR1, SSTR3, SSTR2 KDM1A 4286/4885NPY2R 48/4885NPY4R 77/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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