Rel-Menthone

Rel-Menthone

SCHEMBL3048422

CC(C)[C@H]1CC[C@H](C)CC1=O.CCOC(C)OCC

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
CYP2D6 P10635 1/20 0.32
TLR4 O00206 2/20 0.31
NPC1 O15118 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Rel-Menthone SCHEMBL111746 0.90 LMNA (0.32) LMNACYP2D6
Menthone SCHEMBL3652908 0.90 LMNA (0.32) LMNACYP2D6
Menthone SCHEMBL901274 0.84 TLR4 (0.39) TLR4NPC1L3MBTL1
Menthone SCHEMBL4395963 0.84 TLR4 (0.39) TLR4NPC1L3MBTL1
Rel-Isomenthone SCHEMBL650578 0.84 TLR4 (0.39) TLR4NPC1L3MBTL1
Menthone SCHEMBL21709 0.84 TLR4 (0.39) TLR4NPC1L3MBTL1
Menthone SCHEMBL13255148 0.84 TLR4 (0.39) TLR4NPC1L3MBTL1
Rel-Menthone SCHEMBL1868327 0.84 TLR4 (0.39) TLR4NPC1L3MBTL1
Rel-Menthone SCHEMBL21711 0.84 TLR4 (0.39) TLR4NPC1L3MBTL1
Menthone SCHEMBL12326763 0.84 TLR4 (0.39) TLR4NPC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117355218-A Flavor beads and methods of making and using the same 威·曼父子有限公司 2024-01-05 CN disclosed
CN-101242807-B Mouth-moistening compositions, delivery systems comprising the same, and methods of making the same KRAFT FOODS GLOBAL BRANDS LLC 2014-12-10 CN disclosed
US-8735609-B2 Bryostatin analogues, synthetic methods and uses THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2014-05-27 US disclosed
US-8497385-B2 Bryostatin analogues, synthetic methods and uses THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2013-07-30 US disclosed
US-20130123518-A1 Bryostatin Analogues, Synthetic Methods and Uses THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2013-05-16 US disclosed
CN-101522221-B Process for manufacturing a delivery system for an active component being part of an edible composition KRAFT FOODS GLOBAL BRANDS LLC 2013-04-24 CN disclosed
CN-101282707-B Cooling compositions comprising menthyl esters KRAFT FOODS GLOBAL BRANDS LLC 2013-03-27 CN disclosed
US-8344025-B2 Oxalic acid derivatives and use thereof as physiological cooling active ingredients SYMRISE AG (DE) 2013-01-01 US disclosed
US-8242289-B2 Alkyl-substituted tetrahydropyrans as flavoring substances SYMRISE AG (DE) 2012-08-14 US disclosed
US-20100280262-A1 BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2010-11-04 US disclosed
CN-101242807-A Mouth-moistening compositions, delivery systems comprising the same, and methods of making the same CADBURY ADAMS USA LLC (US) 2008-08-13 CN disclosed
US-20070270485-A1 Byrostatin analogues, synthetic methods and uses THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2007-11-22 US disclosed
US-7256286-B2 Bryostatin analogues, synthetic methods and uses THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2007-08-14 US disclosed
EP-1233956-A4 BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES UNIV LELAND STANFORD JUNIOR (US) 2006-07-05 EP disclosed
US-20030220334-A1 Byrostatin analogues, synthetic methods and uses NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-11-27 US disclosed
US-6624189-B2 Anticancer agents THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2003-09-23 US disclosed
WO-2003070719-A1 BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2003-08-28 WO disclosed
US-20020137789-A1 Byrostatin analogues, synthetic methods and uses NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-09-26 US disclosed
EP-1233956-A1 BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2002-08-28 EP disclosed
WO-2001040214-A1 BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2001-06-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030220334-A1 Byrostatin analogues, synthetic methods and uses BID, HASPIN, HPGDS LMNA 1818/4885CYP2D6 3906/4885TLR4 4438/4885
US-20070270485-A1 Byrostatin analogues, synthetic methods and uses BID, HASPIN, HPGDS LMNA 1818/4885CYP2D6 3906/4885TLR4 4438/4885
US-20020137789-A1 Byrostatin analogues, synthetic methods and uses BID, IGF2BP1, IGFBP4 LMNA 1557/4885CYP2D6 4281/4885TLR4 4487/4885
US-20100280262-A1 BRYOSTATIN ANALOGUES, SYNTHETIC METHODS AND USES MCL1, PBK, BID LMNA 2826/4885CYP2D6 4342/4885TLR4 3966/4885
US-20130123518-A1 Bryostatin Analogues, Synthetic Methods and Uses MCL1, PBK, BID LMNA 2826/4885CYP2D6 4342/4885TLR4 3966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.