SCHEMBL30484221

SCHEMBL30484221

CCCCC(=O)CCN=C=S

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.52
MAPT P10636 1/20 0.41
KMT2A Q03164 1/20 0.41
KEAP1 Q14145 2/20 0.40
NFE2L2 Q16236 2/20 0.40
CES1 P23141 2/20 0.39
CES2 O00748 1/20 0.39
MIF P14174 3/20 0.38
ALDH1A1 P00352 3/20 0.37
TP53 P04637 2/20 0.37
LMNA P02545 1/20 0.37
BACH1 O14867 1/20 0.37
MAFK O60675 1/20 0.37
EGFR P00533 1/20 0.37
PTGS2 P35354 1/20 0.37
TRPA1 O75762 5/20 0.36
GSK3B P49841 1/20 0.36
CA1 P00915 1/20 0.35
IAPP P10997 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3119816 0.90 NAAA (0.61) NAAAMAPTKMT2AKEAP1NFE2L2
SCHEMBL3115794 0.84 NAAA (0.52) NAAAMAPTKMT2AKEAP1NFE2L2
SCHEMBL3128515 0.82 NAAA (0.55) NAAAMAPTKMT2AKEAP1NFE2L2
SCHEMBL978201 0.82 NAAA (0.43) NAAAMAPTKMT2AKEAP1NFE2L2
SCHEMBL11077005 0.80 MAPT (0.41) MAPTKMT2ACES1CES2ALDH1A1
SCHEMBL25333089 0.79 TRPA1 (0.60) NAAAKEAP1NFE2L2MIFALDH1A1
SCHEMBL25330837 0.77 TRPA1 (0.62) NAAAMAPTKMT2AKEAP1NFE2L2
SCHEMBL21777580 0.76 NAAA (0.47) NAAAMAPTKMT2ACES1CES2
SCHEMBL3120743 0.76 NAAA (0.52) NAAAKEAP1NFE2L2MIFALDH1A1
SCHEMBL31412575 0.75 KEAP1 (0.34) NAAAKEAP1NFE2L2MIFALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023133494-A2 OIL-BASED ISOTHIOCYANATE PRODUCTS AND PROCESSES FOR PREPARING OIL-BASED ISOTHIOCYANATE PRODUCTS BRASSICA PROTECTION PRODUCTS LLC (US) 2023-07-13 WO disclosed