Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 16/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13390440 | 0.80 | CYP11B2 (0.53) | CYP11B2PDE10ANPC1RAB9A | |
| SCHEMBL258972 | 0.79 | EGLN2 (0.50) | CYP11B2PDE10ANPC1RAB9A | |
| SCHEMBL2036746 | 0.77 | PDE10A (0.49) | CYP11B2PDE10A | |
| SCHEMBL27038600 | 0.76 | AHR (0.54) | CYP11B2 | |
| SCHEMBL27038055 | 0.76 | NUDT1 (0.35) | — | |
| SCHEMBL3300546 | 0.76 | NUDT1 (0.57) | CYP11B2PDE10A | |
| SCHEMBL13218425 | 0.76 | CYP11B2 (0.45) | CYP11B2HTTPDE10A | |
| SCHEMBL30485249 | 0.72 | NUDT1 (0.33) | PDE10A | |
| SCHEMBL20512222 | 0.72 | ALDH1A1 (0.55) | CYP11B2PDE10AKMT2A | |
| SCHEMBL13409733 | 0.72 | CYP11B2 (0.42) | CYP11B2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118215664-B | Substituted triazoloheteroaryl compounds as USP1 inhibitors and uses thereof | 上海瑛派药业有限公司 | 2025-05-06 | — | — | CN | disclosed |
| EP-4419522-A1 | SUBSTITUTED TRIAZOLOHETEROARYL COMPOUNDS AS USP1 INHIBITORS AND THE USE THEREOF | Impact Therapeutics (Shanghai), Inc (CN) | 2024-08-28 | — | — | EP | disclosed |
| CN-118215664-A | Substituted triazoloheteroaryl compounds as USP1 inhibitors and uses thereof | 上海瑛派药业有限公司 | 2024-06-18 | — | — | CN | disclosed |
| WO-2023066299-A1 | SUBSTITUTED TRIAZOLOHETEROARYL COMPOUNDS AS USP1 INHIBITORS AND THE USE THEREOF | IMPACT THERAPEUTICS (SHANGHAI) , INC (CN) | 2023-04-27 | — | — | WO | disclosed |