SCHEMBL30485666

SCHEMBL30485666

COc1ccc(-c2cccc(Br)c2N)c(F)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 1/20 0.46
CYP3A4 P08684 2/20 0.43
ALDH1A1 P00352 2/20 0.43
GRM2 Q14416 1/20 0.41
PRKCZ Q05513 1/20 0.41
AMY1A P0DUB6 3/20 0.40
PRKAB2 O43741 1/20 0.38
PRKAG1 P54619 1/20 0.38
PRKAA2 P54646 1/20 0.38
PRKAA1 Q13131 1/20 0.38
PRKAG3 Q9UGI9 1/20 0.38
PRKAG2 Q9UGJ0 1/20 0.38
PRKAB1 Q9Y478 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2E1 P05181 1/20 0.38
CYP2C8 P10632 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2A6 P11509 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3723167 0.79 HSP90AA1 (0.47) CYP3A4ALDH1A1SMN1; SMN2CYP1A2CYP2D6
SCHEMBL10340365 0.78 AMY1A (0.50) CD274CYP3A4ALDH1A1GRM2PRKCZ
SCHEMBL22537008 0.77 NPC1 (0.55) CD274CYP3A4ALDH1A1GRM2AMY1A
Hydrochloric Acid SCHEMBL30823011 0.76 PRKAB2 (0.50) CD274GRM2PRKCZPRKAB2PRKAG1
SCHEMBL18436302 0.76 CD274 (0.48) CD274CYP3A4ALDH1A1GRM2AMY1A
SCHEMBL1528920 0.72 CD274 (0.48) CD274CYP3A4ALDH1A1GRM2PRKCZ
SCHEMBL14335108 0.72 MEN1 (0.43) CD274CYP3A4ALDH1A1GRM2SMN1; SMN2
SCHEMBL21840787 0.71 SCN2A (0.49) CYP3A4ALDH1A1SMN1; SMN2CYP1A1CYP1A2
SCHEMBL30125062 0.71 GPR3 (0.52) CYP3A4ALDH1A1SMN1; SMN2CYP1A1CYP1A2
SCHEMBL14334893 0.71 CD274 (0.36) CD274ALDH1A1GRM2SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116265468-A Organic electroluminescent material and device 环球展览公司 2023-06-20 CN disclosed