Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30486 | 0.79 | IDO1 (0.48) | IDO1KMT2AMEN1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL999376 | 0.78 | IDO1 (0.47) | IDO1KMT2AMEN1KDM4EMAPT | |
| Pyrrole SCHEMBL27612136 | 0.73 | IDO1 (0.42) | IDO1TDP1ALDH1A1 | |
| SCHEMBL1103717 | 0.71 | GAA (0.78) | PTPRCCTSLCTSSPTPN13GAA | |
| SCHEMBL29746876 | 0.71 | GAA (0.78) | PTPRCCTSLCTSSPTPN13GAA | |
| SCHEMBL4141797 | 0.69 | RAF1 (0.40) | IDO1TDO2 | |
| SCHEMBL29563426 | 0.69 | IDO1 (0.54) | IDO1TDP1NPC1MAPK1RAB9A | |
| SCHEMBL276443 | 0.69 | IDO1 (0.54) | IDO1TDP1NPC1MAPK1RAB9A | |
| SCHEMBL17255318 | 0.69 | HASPIN (0.45) | TDO2 | |
| SCHEMBL5915065 | 0.67 | TDP2 (0.81) | PTPRCCTSLCTSSPTPN13GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710689-B1 | Polymeric antitumor agents | WYETH CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-5609867-A | POLYAMIDES FROM DIAMINE MONOMERS CONTAINING ANTHRAQUINONE, ANTHRAPYRAZOLE, AZA-ANTHRAQUINONE, AND DIAZA-ANTHRAQUINONE RINGS | AMERICAN CYANAMID COMPANY (US) | 1997-03-11 | — | — | US | disclosed |
| EP-0710689-A2 | Polymeric antitumor agents | American Cyanamid Company (US) | 1996-05-08 | — | — | EP | disclosed |