Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29067515 | 1.00 | TSHR (0.46) | TSHRTP53KCNH3MEN1KMT2A | |
| SCHEMBL29067521 | 0.81 | TGM2 (0.46) | TSHRTP53KCNH3MEN1KMT2A | |
| SCHEMBL17604272 | 0.78 | MAPT (0.49) | TSHRTP53KCNH3MEN1KMT2A | |
| SCHEMBL30486181 | 0.77 | CA1 (0.47) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29067520 | 0.77 | CA1 (0.47) | MEN1KMT2ARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29067514 | 0.76 | CA2 (0.49) | POLB | |
| SCHEMBL29067518 | 0.76 | TDP1 (0.40) | TSHRTP53KCNH3MEN1KMT2A | |
| SCHEMBL631776 | 0.72 | KCNH3 (0.64) | TSHRTP53KCNH3MEN1KMT2A | |
| SCHEMBL12845565 | 0.71 | MTNR1B (0.50) | TSHRTP53KCNH3MEN1KMT2A | |
| SCHEMBL5088995 | 0.71 | KMT2A (0.49) | TSHRTP53KCNH3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116462598-B | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2024-08-09 | — | — | CN | disclosed |
| CN-116462598-A | Allyl arylamine compound and preparation method and application thereof | 成都市第二人民医院 | 2023-07-21 | — | — | CN | disclosed |