Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 5/20 | 0.50 |
| ▸ | PRKCI | P41743 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15934245 | 0.88 | TYR (0.67) | TYRPRKCITSHRCASP1MAPT | |
| SCHEMBL1176667 | 0.86 | TYR (0.66) | TYRPRKCITSHRCASP1MAPT | |
| SCHEMBL12464064 | 0.85 | TYR (0.69) | TYRTSHRCASP1MAPTCYP3A4 | |
| SCHEMBL5381058 | 0.83 | PRKCI (0.63) | PRKCITSHRCASP1CYP3A4ACHE | |
| SCHEMBL454663 | 0.83 | CASP1 (0.52) | TYRPRKCITSHRCASP1MAPT | |
| SCHEMBL23412633 | 0.83 | RECQL (0.58) | TYRPRKCITSHRCASP1MAPT | |
| SCHEMBL29780621 | 0.83 | RECQL (0.58) | TYRPRKCITSHRCASP1MAPT | |
| Hydrochloric Acid SCHEMBL2857849 | 0.81 | ACHE (0.53) | PRKCITSHRCASP1MAPTCYP3A4 | |
| SCHEMBL6152292 | 0.81 | TYR (0.46) | TYRPRKCITSHRCASP1MAPT | |
| SCHEMBL4576433 | 0.80 | PRKCI (0.44) | PRKCITSHRCASP1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107817649-B | Photosensitive resin composition, polyamide resin and method for producing same, compound and method for producing same, cured film and method for producing same | 东京应化工业株式会社 | 2022-09-16 | — | — | CN | disclosed |
| CN-107817649-A | Photosensitive polymer combination, polyamide and its manufacture method, compound and its manufacture method, cured film and its manufacture method | 东京应化工业株式会社 | 2018-03-20 | — | — | CN | disclosed |
| CN-107428747-A | Substituted pyridobenzodiazepine ketone derivative and use thereof | 拜耳制药股份公司 | 2017-12-01 | — | — | CN | disclosed |
| EP-3223821-A1 | SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2017-10-04 | — | — | EP | disclosed |
| US-20170253602-A1 | SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-07 | — | — | US | disclosed |
| US-20170253602-A1 | SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-07 | — | — | US | disclosed |
| US-20170253602-A1 | SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-07 | — | — | US | disclosed |
| WO-2016083276-A1 | SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-02 | — | — | WO | disclosed |
| WO-2016083276-A1 | SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-06-02 | — | — | WO | disclosed |
| US-9018209-B2 | Compounds and methods for the treatment of viruses and cancer | YALE UNIVERSITY (US) | 2015-04-28 | — | — | US | disclosed |
| US-20100222352-A1 | Compounds and Methods for the Treatment of Viruses and Cancer | YALE UNIVERSITY (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100222386-A1 | SUBSTITUTED PIPERIDINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | US | disclosed |
| US-7767695-B2 | Substituted piperidines | HIGH POINT PHARMACEUTICALS, LLC (US) | 2010-08-03 | — | — | US | disclosed |
| EP-1434765-B1 | SUBSTITUTED PIPERIDINES WITH SELECTIVE BINDING TO HISTAMINE H3-RECEPTOR | HIGH POINT PHARMACEUTICALS LLC (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2007038387-A2 | COMPOUNDS AND METHODS FOR THE TREATMENT OF VIRUSES AND CANCER | YALE UNIVERSITY (US) | 2007-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222386-A1 | SUBSTITUTED PIPERIDINES | HRH3, HRH4, HRH2 | TYR 514/4885PRKCI 2744/4885TSHR 792/4885 |
| US-20100222352-A1 | Compounds and Methods for the Treatment of Viruses and Cancer | RCOR1, RCOR3, CCNT1 | TYR 2567/4885PRKCI 4244/4885TSHR 91/4885 |
| US-20170253602-A1 | SUBSTITUTED PYRIDOBENZODIAZEPINONE-DERIVATIVES AND USE THEREOF | BDKRB2, BDKRB1, PDGFRB | TYR 150/4885PRKCI 4187/4885TSHR 2518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.