Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLL | Q9UGP5 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487605 | 0.78 | MAOA (0.54) | ALDH1A1KDM4EGAASMN1; SMN2MAPT | |
| SCHEMBL12765037 | 0.78 | ALDH1A1 (0.45) | POLLALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30487578 | 0.72 | MAOA (0.62) | POLLALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30487601 | 0.70 | POLL (1.00) | POLL | |
| SCHEMBL3451196 | 0.68 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL20480377 | 0.68 | HTR2C (0.56) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL28370465 | 0.68 | POLL (0.70) | POLLALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11969377 | 0.68 | ALOX5 (0.40) | KDM4EMAPTKMT2AACHETP53 | |
| SCHEMBL3410798 | 0.67 | KDM4E (0.76) | POLLALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL18213636 | 0.67 | ELANE (0.40) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110872268-B | Isocoumarin derivative and preparation method and medicinal application thereof | 复旦大学 | 2023-07-25 | — | — | CN | disclosed |