Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25271191 | 1.00 | ALDH1A1 (0.39) | ALDH1A1CYP3A4GAASIRT1MAPT | |
| SCHEMBL6998660 | 0.80 | NOTUM (0.41) | — | |
| Hydrochloric Acid SCHEMBL10812623 | 0.77 | SIRT1 (0.34) | ALDH1A1CYP3A4GAASIRT1MAPT | |
| Hydrochloric Acid SCHEMBL10812630 | 0.77 | SIRT1 (0.34) | ALDH1A1CYP3A4GAASIRT1MAPT | |
| Hydrochloric Acid SCHEMBL10927052 | 0.74 | HTR2A (0.33) | — | |
| SCHEMBL29992013 | 0.74 | KMT2A (0.47) | ALDH1A1LMNA | |
| SCHEMBL7445124 | 0.74 | CA1 (0.49) | ALDH1A1CYP3A4MAPT | |
| SCHEMBL27468308 | 0.74 | BRD4 (0.42) | ALDH1A1MAPTLMNA | |
| SCHEMBL30188537 | 0.73 | FAAH (0.44) | ALDH1A1GAAMAPTLMNA | |
| SCHEMBL1030609 | 0.73 | FAAH (0.44) | ALDH1A1GAAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |