Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | ATF1 | P18846 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107445 | 1.00 | TSHR (0.33) | TSHRSLC6A9MLYCDATF1NFKB1 | |
| SCHEMBL903465 | 0.79 | PKM (0.37) | TSHRHPGDMCOLN3NPSR1KDM4E | |
| SCHEMBL30488144 | 0.78 | NR1H2 (0.36) | TSHRMLYCDATF1NFKB1NPSR1 | |
| SCHEMBL14107459 | 0.78 | NR1H2 (0.36) | TSHRMLYCDATF1NFKB1NPSR1 | |
| SCHEMBL14107454 | 0.70 | MLYCD (0.52) | MLYCDHPGDMCOLN3NPSR1KDM4E | |
| SCHEMBL5787508 | 0.70 | SIRT3 (0.37) | TSHRHPGDMCOLN3NPSR1KDM4E | |
| SCHEMBL31462730 | 0.70 | TRPV4 (0.34) | TSHRHPGDKDM4EALDH1A1LMNA | |
| SCHEMBL3873731 | 0.69 | HDAC8 (0.39) | HPGDALDH1A1 | |
| SCHEMBL2490048 | 0.69 | ALDH1A1 (0.32) | ALDH1A1LMNA | |
| SCHEMBL30686033 | 0.68 | SRC (0.44) | TSHRHPGDMCOLN3NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107630-A2 | AMINO ALCOHOL COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |